PRKAR2B

Gene Symbol PRKAR2B
Entrez Gene 5577
Alt Symbol PRKAR2, RII-BETA
Species Human
Gene Type protein-coding
Description protein kinase, cAMP-dependent, regulatory, type II, beta
Other Description H_RG363E19.2|WUGSC:H_RG363E19.2|cAMP-dependent protein kinase type II-beta regulatory chain|cAMP-dependent protein kinase type II-beta regulatory subunit
Swissprots A4D0R9 P31323
Accessions AAC08318 AAS07389 ABO15447 EAL24395 EAW83390 EAW83391 P31323 AK128639 BAG54705 AK291441 BAF84130 AL559918 AM392728 CAL37606 AM392771 CAL37649 AM393258 CAL38136 AM393700 CAL38576 BC014355 BC075800 AAH75800 BQ022817 CA405423 CF593944 M31158 AAA60099 XM_011516398 XP_011514700 XM_011516399 XP_011514701 NM_002736 NP_002727
Function Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:21423175}. Cell membrane {ECO:0000269|PubMed:21423175}. Note=Colocalizes with PJA2 in the cytoplasm and at the cell membrane.
Tissue Specificity Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
Top Pathways Apoptosis, Insulin signaling pathway

PKA IIβ reg siRNA (h) - sc-39166 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PKA IIβ reg shRNA Plasmid (h) - sc-39166-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PKA IIβ reg shRNA (h) Lentiviral Particles - sc-39166-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PKA 2 beta RNAi - H00005577-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU025831 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® siRNA - SIHK1817 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1815 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1816 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN17421 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17421 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PRKAR2B siRNA (Human) - CRH3747 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Prkar2b (NM_002736.2) - SHH382768 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PRKAR2B(NM_002736.2) - SHR140226 from Creative biogene

Category siRNA
Species Reactivities Human

PRKAR2B shRNA Plasmid (Human) - CHH3747 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PRKAR2B miRNA 3'UTR clone - MiUTR1H-08269 from Creative biogene

Species Reactivities Human
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