VEGFC

Gene Symbol VEGFC
Entrez Gene 7424
Alt Symbol Flt4-L, LMPH1D, VRP
Species Human
Gene Type protein-coding
Description vascular endothelial growth factor C
Other Description FLT4 ligand DHM|vascular endothelial growth factor-related protein
Swissprots B2R9Q8 P49767
Accessions AAB82540 CAH23418 CAI59112 CAI63838 CAI84578 CAJ29667 CAJ32890 CAJ32903 CAL32724 CAV32970 CBH30535 EAX04717 P49767 AK313879 BAG36605 AW294939 BC035212 AAH35212 BC063685 AAH63685 BF528469 CR541897 CAG46695 DA044965 DQ891162 ABM82088 DQ893345 ABM84271 DQ894481 ABM85407 DQ896666 ABM87665 U43142 AAA85214 U58111 AAB02909 X94216 CAA63907 NM_005429 NP_005420
Function Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. {ECO:0000269|PubMed:20145116}.
Subcellular Location Secreted.
Tissue Specificity Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte.
Top Pathways Cytokine-cytokine receptor interaction, Focal adhesion, PI3K-Akt signaling pathway, TNF signaling pathway, Rap1 signaling pathway

VEGF-C Antibody - 2445 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of recombinant human VEGF-C protein at various concentrations, using VEGF-C Antibody.

VEGF-C (E-6) - sc-374628 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VEGF-C (E-6): sc-374628. Immunofluorescence staining of methanol-fixed HeLa cells showing cell surface localization.

VEGF-C (C-20) - sc-1881 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VEGF-C (C-20): sc-1881. Immunofluorescence staining of methanol-fixed RAW 264.7 cells showing cytoplasmic localization.

VEGF-C (A-5) - sc-74584 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VEGF-C (A-5): sc-74584. Western blot analysis of human recombinant VEGF-C.

VEGF-C (A-16) - sc-27128 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VEGF-C (A-16): sc-27128. Western blot analysis of VEGF-C expression in non-transfected: sc-117752 (A) and human VEGF-C transfected: sc-113917 (B) 293T whole cell lysates.

VEGF-C (F-10) - sc-74585 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VEGF-C (F-10): sc-74585. Western blot analysis of human recombinant VEGF-C.

VEGF-C (F-5) - sc-398004 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VEGF-C (F-5): sc-398004. Western blot analysis of VEGF-C expression in non-transfected 293T: sc-117752 (A), human VEGF-C transfected 293T: sc-116733 (B) and MH-S (C) whole cell lysates.

VEGF-C (N-19) - sc-7133 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VEGF-C (N-19): sc-7133. Immunofluorescence staining of methanol-fixed RAW 264.7 cells showing cytoplasmic localization.

VEGF-C (H-48) - sc-25783 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
VEGF-C (H-48): sc-25783. Western blot analysis of VEGF-C expression in non-transfected: sc-117752 (A) and human VEGF-C transfected: sc-113917 (B) 293T whole cell lysates.

VEGF-C (H-190) - sc-9047 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
VEGF-C (H-190): sc-9047. Western blot analysis of VEGF-C expression in MCF7 whole cell lysate.

VEGF-C (30AT1174.77.260) - sc-130289 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
VEGF-C (30AT1174.77.260): sc-130289. Western blot analysis of VEGF-C expression in HDMEC whole cell lysates.

VEGF-C (MM0006-2E65) - sc-101583 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-VEGFC antibody - ab9546 from Abcam

Prices $391.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot with human and rat VEGF C and VEGF D using the polyclonal anti VEGF C antibody ab9546. Proteins were separated by 15% SDS-PAGE and blotted on to PVDF membranes as described. After transfer, the membrane was incubated for 1 h with ab9546 at 1 µg/ml in TBS containing 20% non-fat milk followed by incubation with a goat-anti-rabbit alkaline phosphatase-conjugated secondary antibody.  Lane 1/250ng rat VEGF C; lane 2/250 ng human VEGF C; lane 3/250 ng rat VEGF D; lane4/250 ng human VEGF-D.

Anti-VEGFC antibody - ab83905 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-VEGFC antibody (ab83905) at 1 µg/ml + MCF7 (Human breast adenocarcinoma cell line) Whole Cell Lysate at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-VEGFC antibody - ab135506 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-VEGFC antibody (ab135506) at 1/100 dilution + 293 cell lysate at 12.5 µg

Anti-VEGFC antibody - ab18883 from Abcam

Prices $370.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-VEGFC antibody - ab135505 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-VEGFC antibody (ab135505) at 1/50 dilutionLane 1 : Lysate of non-transfected 293 cellsLane 2 : Lysate of 293 cells transiently transfected with the VEGF3 gene Lysates/proteins at 2 µg per lane.

Anti-VEGFC antibody - ab190613 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-VEGFC antibody (ab190613) at 1/500 dilution + L929 cell extract at 30 µg

Anti-VEGFC antibody [197CT7.3.4] - ab191274 from Abcam

Prices $376.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human small intestine tissue labeling VEGFC with ab191274 at 1/50 dilution.

Anti-VEGFC antibody [4A1] - ab140803 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4A1
All lanes : Anti-VEGFC antibody [4A1] (ab140803) at 1/200 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cells transfected with pCMV6-ENTRY VEGFC cDNALysates/proteins at 5 µg per lane.

Anti-VEGFC antibody [9/E7] - ab106512 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 9/E7
Immunohistochemistry (Frozen sections) analysis of rat mammary tumor tissue sections labelling VEGFC with ab106512.

Anti-VEGFC antibody [mAbcam 63221] - ab63221 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone mAbcam 63221
All lanes : Anti-VEGFC antibody [mAbcam 63221] (ab63221) at 10 µg/mlLane 1 : Spleen (Human) Tissue Lysate - adult normal tissue (ab29699)Lane 2 : Lymph node (Human) Tissue Lysate - adult normal tissue (ab29871)Lane 3 : Thymus (Human) Tissue Lysate - adult normal tissue (ab30146)Lane 4 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lane 5 : HEK293 (Human embryonic kidney cell line) Whole Cell LysateLysates/proteins at 20 µg per lane.SecondaryGoat polyclonal to Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-VEGFC antibody [mAbcam 63221] (FITC) - ab150262 from Abcam

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone mAbcam 63221

Anti-VEGFC Antibody (N-Terminus) - LS-C345756 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of VEGFC Antibody with human 786-0 Whole Cell lysate.

Anti-VEGFC Antibody - LS-C330947 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of 293 cell lines, using VEGFC antibody.
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