Gene Symbol | VEGFC |
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Entrez Gene | 7424 |
Alt Symbol | Flt4-L, LMPH1D, VRP |
Species | Human |
Gene Type | protein-coding |
Description | vascular endothelial growth factor C |
Other Description | FLT4 ligand DHM|vascular endothelial growth factor-related protein |
Swissprots | B2R9Q8 P49767 |
Accessions | AAB82540 CAH23418 CAI59112 CAI63838 CAI84578 CAJ29667 CAJ32890 CAJ32903 CAL32724 CAV32970 CBH30535 EAX04717 P49767 AK313879 BAG36605 AW294939 BC035212 AAH35212 BC063685 AAH63685 BF528469 CR541897 CAG46695 DA044965 DQ891162 ABM82088 DQ893345 ABM84271 DQ894481 ABM85407 DQ896666 ABM87665 U43142 AAA85214 U58111 AAB02909 X94216 CAA63907 NM_005429 NP_005420 |
Function | Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. {ECO:0000269|PubMed:20145116}. |
Subcellular Location | Secreted. |
Tissue Specificity | Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte. |
Top Pathways | Cytokine-cytokine receptor interaction, Focal adhesion, PI3K-Akt signaling pathway, TNF signaling pathway, Rap1 signaling pathway |
Active human VEGFC full length protein - ab155739 from Abcam
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Active human VEGFC full length protein - ab51968 from Abcam
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Active rat VEGFC full length protein - ab52146 from Abcam
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Human VEGFC full length protein - ab83573 from Abcam
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Human VEGFC full length protein - ab152061 from Abcam
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Human VEGFC peptide - ab95850 from Abcam
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Human VEGFC peptide - ab97415 from Abcam
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Mouse VEGFC full length protein - ab51947 from Abcam
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VEGFC Antibody Blocking Peptide - LS-E1322 from LifeSpan Bioscience
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VEGFC Antibody Blocking Peptide - LS-E6826 from LifeSpan Bioscience
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VEGFC Antibody Blocking Peptide - LS-E23056 from LifeSpan Bioscience
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VEGF-C Partial Recombinant Protein - H00007424-Q01 from Novus Biologicals
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VEGF-C Recombinant Protein - H00007424-P01 from Novus Biologicals
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VEGF-C Recombinant Protein - P4111 from Novus Biologicals
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VEGF-C Protein - NBP1-99429 from Novus Biologicals
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VEGF-C Protein - NBP1-99740 from Novus Biologicals
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VEGF3-Antibody-N-term-Blocking-peptide - BP11951a from Abgent, a WuXi AppTec company
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VEGFC-VEGF3-Antibody-Center-M263-Blocking-peptide - BP2042c from Abgent, a WuXi AppTec company
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VEGFC recombinant protein - GTX65280 from GeneTex
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VEGFC recombinant protein - GTX65279 from GeneTex
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VEGFC Recombinant Protein - GTX48342-PRO from GeneTex
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Recombinant Human VEGF-C - 2179-VC-025 from R&D Systems
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Recombinant Human VEGF-C, CF - 2179-VC-025/CF from R&D Systems
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Recombinant Human VEGF-C (Cys156Ser) - 752-VC-025 from R&D Systems
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Recombinant Human VEGF-C (Cys156Ser), CF - 752-VC-025/CF from R&D Systems
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