RYBP

Gene Symbol	RYBP
Entrez Gene	23429
Alt Symbol	AAP1, DEDAF, YEAF1
Species	Human
Gene Type	protein-coding
Description	RING1 and YY1 binding protein
Other Description	APAP-1|DED-associated factor|RING1 and YY1-binding protein|YY1 and E4TF1 associated factor 1|YY1 and E4TF1-associated factor 1|apoptin-associating protein 1|death effector domain-associated factor|ring1 interactor RYBP
Swissprots	Q9UMW4 Q9P2W5 Q8N488
Accessions	CCQ43407 EAW65515 EAW65516 EAW65517 Q8N488 AB029551 BAA89486 AF085840 AF179286 AAD51858 AF227959 AAK63197 AL049940 AY228125 AAO73587 BC014959 AAH14959 BC036459 AAH36459 BF939411 DQ892214 ABM83140 DQ895410 ABM86336 XM_011548866 XP_011547168 XM_011548867 XP_011547169 NM_012234 NP_036366
Function	Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. May bind to DNA. Promotes apoptosis. {ECO:0000269|PubMed:11395500, ECO:0000269|PubMed:11953439, ECO:0000269|PubMed:14765135, ECO:0000269|PubMed:19098711}.
Subcellular Location	Nucleus. Cytoplasm. Nucleus, nucleoplasm {ECO:0000250}. Note=Primarily found in the nucleus. Detected in a punctate pattern likely to represent Polycomb group (PcG) bodies (By similarity). {ECO:0000250}.
Tissue Specificity	Widely expressed with highest levels in lymphoid tissues and placenta. {ECO:0000269|PubMed:11395500, ECO:0000269|PubMed:11953439, ECO:0000269|PubMed:14765135}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RYBP full length protein - ab153229 from Abcam Category Protein Source Wheat germ Species Human

RYBP peptide - ab6097 from Abcam Category Peptide

RYBP Antibody Blocking Peptide - LS-E4332 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RYBP Antibody Blocking Peptide - LS-E11098 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RYBP Antibody Blocking Peptide - LS-E14049 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RYBP Antibody Blocking Peptide - LS-E14048 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RYBP Antibody Blocking Peptide - LS-E29920 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

RYBP Antibody Blocking Peptide - LS-E13362 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RYBP/DEDAF Recombinant Protein - H00023429-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

RYBP/DEDAF Blocking Peptide - NBP1-76842PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Recombinant Human RYBP/DEDAF Protein - NBP1-98929 from Novus Biologicals Category Protein Prices $269.00 Sizes 20 µg Source E. coli Species Human

RYBP-Antibody-N-term-Blocking-Peptide - BP16629a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DEDAF peptide - GTX26097 from GeneTex Category Peptide Prices $179.00 Sizes 50 μg Species Human

Human RYBP protein - orb169225 from Biorbyt Category Protein Prices $170.00, $289.00, $1,139.00 Sizes 2 μg, 10 μg, 100 μg Species Human

Human AAP1 protein (GST Tag) - orb138112 from Biorbyt Category Protein Source Baculovirus-Insect Cells Species Human

RYBP protein (His tag) - 80R-2340 from Fitzgerald Category Protein Prices $270.00 Sizes 20 µg Source E.coli

RYBP (1-228, His-tag) - AR50424PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

RYBP (1-228, His-tag) - AR50424PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

RYBP - H00023429-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

RYBP Control Peptide - AP30284CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

RYBP, 1-228aa, Human, His tag, E.coli - 01-P1600 from ARP American Research Products Category Protein Prices $139.00, $369.00, $849.00 Sizes 5 µg, 20 µg, 100 µg Species Human

DEDAF Peptide - 2227P from ProSci Category Peptide Species Human

RYBP fusion protein - ag1908 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

RYBP Human - PRPS-1146 from NeoScientific Category Protein Prices $65.00, $169.00, $1,560.00 Sizes 2 µg, 10 µg, 100 µg Source E.coli. Species Human

Recombinant Human RYBP Protein - BP002260-PRO-1139 from Syd Labs Category Protein Prices $160.00, $1,200.00 Sizes 10 µg, 100 µg Source E. coli-derived. Species Human

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