RYBP

Gene Symbol RYBP
Entrez Gene 23429
Alt Symbol AAP1, DEDAF, YEAF1
Species Human
Gene Type protein-coding
Description RING1 and YY1 binding protein
Other Description APAP-1|DED-associated factor|RING1 and YY1-binding protein|YY1 and E4TF1 associated factor 1|YY1 and E4TF1-associated factor 1|apoptin-associating protein 1|death effector domain-associated factor|ring1 interactor RYBP
Swissprots Q9UMW4 Q9P2W5 Q8N488
Accessions CCQ43407 EAW65515 EAW65516 EAW65517 Q8N488 AB029551 BAA89486 AF085840 AF179286 AAD51858 AF227959 AAK63197 AL049940 AY228125 AAO73587 BC014959 AAH14959 BC036459 AAH36459 BF939411 DQ892214 ABM83140 DQ895410 ABM86336 XM_011548866 XP_011547168 XM_011548867 XP_011547169 NM_012234 NP_036366
Function Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. May bind to DNA. Promotes apoptosis. {ECO:0000269|PubMed:11395500, ECO:0000269|PubMed:11953439, ECO:0000269|PubMed:14765135, ECO:0000269|PubMed:19098711}.
Subcellular Location Nucleus. Cytoplasm. Nucleus, nucleoplasm {ECO:0000250}. Note=Primarily found in the nucleus. Detected in a punctate pattern likely to represent Polycomb group (PcG) bodies (By similarity). {ECO:0000250}.
Tissue Specificity Widely expressed with highest levels in lymphoid tissues and placenta. {ECO:0000269|PubMed:11395500, ECO:0000269|PubMed:11953439, ECO:0000269|PubMed:14765135}.

RYBP CRISPR/Cas9 KO Plasmid (h) - sc-407140 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RYBP HDR Plasmid (h) - sc-407140-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RYBP Double Nickase Plasmid (h) - sc-407140-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RYBP Double Nickase Plasmid (h2) - sc-407140-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RYBP CRISPR Activation Plasmid (h) - sc-407140-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RYBP CRISPR Activation Plasmid (h2) - sc-407140-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RYBP Lentiviral Activation Particles (h) - sc-407140-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RYBP Lentiviral Activation Particles (h2) - sc-407140-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RYBP siRNA (h) - sc-106751 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RYBP shRNA Plasmid (h) - sc-106751-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RYBP shRNA (h) Lentiviral Particles - sc-106751-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RYBP/DEDAF RNAi - H00023429-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU033911 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18776 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18776 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

RYBP siRNA (Human) - CRH8264 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RYBP - MBS8228302 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RYBP (NM_012234.5) - SHH401008 from Creative biogene

Category siRNA
Species Reactivities Human

Human RYBP siRNA - orb268766 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RYBP shRNA Plasmid (Human) - CHH8264 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RYBP miRNA 3'UTR clone - MiUTR4H-TG07745 from Creative biogene

Species Reactivities Human
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