PDK3

Gene Symbol	PDK3
Entrez Gene	5165
Alt Symbol	CMTX6, GS1-358P8.4
Species	Human
Gene Type	protein-coding
Description	pyruvate dehydrogenase kinase, isozyme 3
Other Description	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial|pyruvate dehydrogenase kinase, isoenzyme 3|pyruvate dehydrogenase, lipoamide, kinase isozyme 3, mitochondrial
Swissprots	Q15120 B4DXG6
Accessions	EAW99019 EAW99020 Q15120 AI001064 AI080664 AK301965 BAG63378 AW173304 BC015948 AAH15948 BC038512 BG717206 BI549903 BU069975 HG512466 L42452 AAC42011 NM_001142386 NP_001135858 NM_005391 NP_005382
Function	Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species. {ECO:0000269|PubMed:10748134, ECO:0000269|PubMed:11486000, ECO:0000269|PubMed:15861126, ECO:0000269|PubMed:16436377, ECO:0000269|PubMed:17683942, ECO:0000269|PubMed:18718909, ECO:0000269|PubMed:22865452}.
Subcellular Location	Mitochondrion matrix.
Tissue Specificity	Expressed in heart, skeletal muscle, spinal cord, as well as fetal and adult brain. {ECO:0000269|PubMed:23297365}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PDK3 - MBS1274637 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC015948

Human PDK3 Gene ORF cDNA clone in cloning vector - HG10723-M from Sino Biological Species Human

Human PDK3 Gene ORF cDNA clone expression plasmid, C-His tag - HG10723-CH from Sino Biological Species Human

Human PDK3 Gene cDNA Clone (full-length ORF Clone) expression ready, untagged - HG10723-M-N from Sino Biological Species Human Accession NM_005391.4

Human PDK3 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10723-ANG from Sino Biological Species Human

Human PDK3 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10723-M-F from Sino Biological Species Human

Human PDK3 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10723-ACR from Sino Biological Species Human

Human PDK3 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10723-ANR from Sino Biological Species Human

Human PDK3 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10723-ACG from Sino Biological Species Human

Human PDK3 Gene ORF cDNA clone expression plasmid - HG10723-UT from Sino Biological Species Human

Human PDK3 Gene ORF cDNA clone expression plasmid, N-His tag - HG10723-NH from Sino Biological Species Human

Human PDK3 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10723-NF from Sino Biological Species Human

Human PDK3 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10723-NM from Sino Biological Species Human

Human PDK3 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10723-CF from Sino Biological Species Human

Human PDK3 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10723-CY from Sino Biological Species Human

Human PDK3 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10723-CM from Sino Biological Species Human

Human PDK3 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10723-NY from Sino Biological Species Human

Human PDK3 ORF clone(NM_005391.4) - CDCL185681 from Creative biogene Species Human

Human PDK3 ORF Clone (BC015948) - CDCS408261 from Creative biogene Species Human Accession Q15120

Human PDK3 gene - orb91231 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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