SOX17

Gene Symbol SOX17
Entrez Gene 64321
Alt Symbol VUR3
Species Human
Gene Type protein-coding
Description SRY (sex determining region Y)-box 17
Other Description SRY-related HMG-box transcription factor SOX17|transcription factor SOX-17
Swissprots Q9H6I2
Accessions EAW86748 Q9H6I2 AB073988 BAB83867 AK025905 BAB15277 BC030209 AAH30209 BC111365 AAI11366 BC111770 AAI11771 BC140307 AAI40308 DA874945 NM_022454 NP_071899
Function Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267}.
Tissue Specificity Expressed in adult heart, lung, spleen, testis, ovary, placenta, fetal lung, and kidney. In normal gastrointestinal tract, it is preferentially expressed in esophagus, stomach and small intestine than in colon and rectum. {ECO:0000269|PubMed:11786926}.
Top Pathways Wnt signaling pathway

Custom Human SOX17 ELISA - ELH-SOX17 from RayBiotech

Category ELISA Kit
Prices $615.00, $1,107.00, $2,460.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

SRY (sex determining region Y) -box 17, ELISA Kit - MBS9318151 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Custom Human SOX17 Elisa kit - orb305398 from Biorbyt

Category ELISA Kit
Prices $1,148.00, $1,981.00, $4,284.00
Sizes 96 assays, 192 assays, 480 assays

Human SOX17 ELISA - RAB1712 from Sigma-Aldrich

Prices $615.00
Sizes 1 kt

Human SOX17 ELISA - ELH-SOX17-1 from RayBiotech

Category ELISA Kit
Prices $615.00, $1,107.00, $2,460.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human SOX17 ELISA Kit - E036582 from Biobool

Category ELISA Kit

anti-SOX17 antibody - ARG56132 from Arigo Biolaboratories

Category ELISA Kit

anti-SOX17 antibody - ARG56133 from Arigo Biolaboratories

Category ELISA Kit
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