SOX17

Gene Symbol	SOX17
Entrez Gene	64321
Alt Symbol	VUR3
Species	Human
Gene Type	protein-coding
Description	SRY (sex determining region Y)-box 17
Other Description	SRY-related HMG-box transcription factor SOX17|transcription factor SOX-17
Swissprots	Q9H6I2
Accessions	EAW86748 Q9H6I2 AB073988 BAB83867 AK025905 BAB15277 BC030209 AAH30209 BC111365 AAI11366 BC111770 AAI11771 BC140307 AAI40308 DA874945 NM_022454 NP_071899
Function	Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267}.
Tissue Specificity	Expressed in adult heart, lung, spleen, testis, ovary, placenta, fetal lung, and kidney. In normal gastrointestinal tract, it is preferentially expressed in esophagus, stomach and small intestine than in colon and rectum. {ECO:0000269|PubMed:11786926}.
Top Pathways	Wnt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SOX17 Antibody Blocking Peptide - LS-E14311 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SOX17 Antibody Blocking Peptide - LS-E26528 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SOX17 blocking peptide - GTX88928-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Rat

SOX17 protein - orb197718 from Biorbyt Category Protein Prices $315.00 Sizes 100 μg Species Human

SOX17 Immunizing peptide - orb50360 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

SOX17 Blocking Peptide - 33R-8221 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SOX17 Blocking Peptide - 33R-3603 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SOX17 Blocking Peptide - abx063948 from Abbexa Category Peptide Species Human, Monkey

SOX17 Peptide - AC21-1364-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Recombinant Human SOX17 - 230-10008 from RayBiotech Category Protein Source Escherichia coli (E.coli) Species Human

SOX17 Peptide - 7917P from ProSci Category Peptide Species Human

SOX17 Peptide - 46-423P from ProSci Category Peptide

SOX17 fusion protein - Ag19045 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

SOX17 fusion protein - Ag19157 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

SOX17 Blocking Peptide - CBP2754 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Monkey

Recombinant Human Transcription factor SOX-17(SOX17) - CSB-YP887989HU CSB-EP887989HU CSB-BP887989HU CSB-MP887989HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SOX17 - TP320888 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SOX17, Peptide - MBS426897 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Rat

SOX17 Recombinant Protein Antigen - NBP2-49549PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

SOX17 Peptide, Human - M34GP14914H from Creative Peptides Category Peptide Source Synthetic. Species Human

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