PLXNA1

Gene Symbol	PLXNA1
Entrez Gene	5361
Alt Symbol	NOV, NOVP, PLEXIN-A1, PLXN1
Species	Human
Gene Type	protein-coding
Description	plexin A1
Other Description	plexin 1|plexin-A1|semaphorin receptor NOV
Swissprots	Q9UIW2
Accessions	EAW79349 EAW79350 EAW79351 Q9UIW2 AI472001 AK054675 AK055605 AK126101 BAC86440 AK127254 AK128612 BAG54700 AK293425 BAG56931 AL136663 BC017323 BC032432 BC042904 BC156129 AAI56130 BC157020 AAI57021 BQ920360 X87832 CAB57274 XM_011512908 XP_011511210 XM_011512909 XP_011511211 NM_032242 NP_115618
Function	Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity	Detected in fetal brain, lung, liver and kidney. {ECO:0000269|PubMed:8570614}.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse Plexin A1 (NP_032907) VersaClone cDNA - RDC0982 from R&D Systems Prices $499.00 Sizes 10 µg Species Mouse

Human Plexin A1 (NP_115618) VersaClone cDNA - RDC0967 from R&D Systems Prices $799.00 Sizes 10 µg Species Human

PLXNA1 - MBS1273433 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC032432

Human PLXNA1 Gene ORF cDNA clone in cloning vector - HG13359-G from Sino Biological Species Human

Human PLXNA1 Gene ORF cDNA clone expression plasmid, N-His tag - HG13359-NH from Sino Biological Species Human

Human PLXNA1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13359-ACR from Sino Biological Species Human

Human PLXNA1 Gene ORF cDNA clone expression plasmid, C-His tag - HG13359-CH from Sino Biological Species Human

Human PLXNA1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13359-ACG from Sino Biological Species Human

Human PLXNA1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13359-NY from Sino Biological Species Human

Human PLXNA1 Gene ORF cDNA clone expression plasmid - HG13359-UT from Sino Biological Species Human

Human PLXNA1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13359-CY from Sino Biological Species Human

Human PLXNA1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13359-NF from Sino Biological Species Human

Human PLXNA1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13359-NM from Sino Biological Species Human

Human PLXNA1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13359-CF from Sino Biological Species Human

Human PLXNA1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13359-CM from Sino Biological Species Human

Mouse PLXNA1 ORF clone (NM_032242.3) - CDCL149452 from Creative biogene Species Human

Human PLXNA1 ORF Clone (BC032432) - CDCS416209 from Creative biogene Species Human Accession Q9UIW2

Human PLXNA1 ORF clone (BC032432) - CDCB159814 from Creative biogene Species Human

Search more