PLXNA1

Gene Symbol PLXNA1
Entrez Gene 5361
Alt Symbol NOV, NOVP, PLEXIN-A1, PLXN1
Species Human
Gene Type protein-coding
Description plexin A1
Other Description plexin 1|plexin-A1|semaphorin receptor NOV
Swissprots Q9UIW2
Accessions EAW79349 EAW79350 EAW79351 Q9UIW2 AI472001 AK054675 AK055605 AK126101 BAC86440 AK127254 AK128612 BAG54700 AK293425 BAG56931 AL136663 BC017323 BC032432 BC042904 BC156129 AAI56130 BC157020 AAI57021 BQ920360 X87832 CAB57274 XM_011512908 XP_011511210 XM_011512909 XP_011511211 NM_032242 NP_115618
Function Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity Detected in fetal brain, lung, liver and kidney. {ECO:0000269|PubMed:8570614}.
Top Pathways Axon guidance

plexin-A1 CRISPR/Cas9 KO Plasmid (h) - sc-403043 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A1 HDR Plasmid (h) - sc-403043-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A1 Double Nickase Plasmid (h) - sc-403043-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A1 Double Nickase Plasmid (h2) - sc-403043-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A1 CRISPR Activation Plasmid (h) - sc-403043-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A1 CRISPR Activation Plasmid (h2) - sc-403043-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A1 Lentiviral Activation Particles (h) - sc-403043-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A1 Lentiviral Activation Particles (h2) - sc-403043-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A1 siRNA (h) - sc-42170 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

plexin-A1 shRNA Plasmid (h) - sc-42170-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

plexin-A1 shRNA (h) Lentiviral Particles - sc-42170-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Plexin A1 RNAi - H00005361-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU118871 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU008741 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17009 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

PLXNA1 siRNA (Human) - CRH3599 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PLXNA1 (NM_032242.3) - SHH378192 from Creative biogene

Category siRNA
Species Reactivities Human

Human PLXNA1 siRNA - orb264101 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLXNA1 shRNA Plasmid (Human) - CHH3599 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLXNA1 miRNA 3'UTR clone - MiUTR3H-03844 from Creative biogene

Species Reactivities Human
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