PLXNA1

Gene Symbol PLXNA1
Entrez Gene 5361
Alt Symbol NOV, NOVP, PLEXIN-A1, PLXN1
Species Human
Gene Type protein-coding
Description plexin A1
Other Description plexin 1|plexin-A1|semaphorin receptor NOV
Swissprots Q9UIW2
Accessions EAW79349 EAW79350 EAW79351 Q9UIW2 AI472001 AK054675 AK055605 AK126101 BAC86440 AK127254 AK128612 BAG54700 AK293425 BAG56931 AL136663 BC017323 BC032432 BC042904 BC156129 AAI56130 BC157020 AAI57021 BQ920360 X87832 CAB57274 XM_011512908 XP_011511210 XM_011512909 XP_011511211 NM_032242 NP_115618
Function Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity Detected in fetal brain, lung, liver and kidney. {ECO:0000269|PubMed:8570614}.
Top Pathways Axon guidance

Human Plexin A1 peptide - ab42757 from Abcam

Category Peptide
Species Human
Immunocytochemical double labelling using anti-Myc mouse monoclonal anti-Plexin A1 rabbit polyclonal antibodies in Cos-7 cells mock transfected (A,D) or transfected with Myc-tagged mouse Plexin A1 construct (B,E). The specificity of the binding protein in E was demonstrated using Plexin A1 peptide (ab42757 at 1µg/ml) in the presence of this Plexin A1 antibody (C,F).

Mouse Plexin A1 peptide - ab34127 from Abcam

Category Peptide

Recombinant human Plexin-A1 (OPCA01351) - OPCA01351 from Aviva Systems Biology

Category Protein
Prices $220.00
Sizes 50 µg
Species Human

Human PLXNA1 protein - orb245586 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

Human PLXNA1 protein - orb246200 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

Plexin A1 protein - 30R-3291 from Fitzgerald

Category Protein
Prices $210.00
Sizes 50 µg
Source E.coli

Recombinant Human PLXNA1 - PLXNA1-509H from Creative Biomart

Category Protein
Source Mammalian Cells
Species Human

Recombinant Plexin A1 (PLXNA1) - RPH354Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant human Plexin-A1 - CSB-EP143094h(B) CSB-BP143094h(B) CSB-MP143094h(B) from Cusabio

Category Protein
Source E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant human Plexin-A1 - CSB-EP143094h(A) CSB-BP143094h(A) CSB-MP143094h(A) from Cusabio

Category Protein
Source E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Human Plexin-A1(PLXNA1) ,partial - CSB-EP883448HU CSB-BP883448HU CSB-MP883448HU from Cusabio

Category Protein
Source E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Human Plexin-A1(PLXNA1),partial - CSB-RP143094h(B) from Cusabio

Category Protein
Source E.coli
Species Human

Recombinant Human Plexin-A1(PLXNA1),partial - CSB-RP143094h(A) from Cusabio

Category Protein
Source E.coli
Species Human

Recombinant Human Plexin-A1(PLXNA1) ,partial - CSB-YP883448HU from Cusabio

Category Protein
Source Yeast
Species Human

Recombinant human Plexin-A1 protein - CSB-RP143074h from Cusabio

Category Protein
Species Human

NOV Protein (OPPB00125) - OPPB00125 from Aviva Systems Biology

Category Protein
Prices $215.00
Sizes 5 µg

Plexin A1 (Sema Domain) - PX1305 from ECM Biosciences

Category Peptide
Prices $55.00
Sizes 50 μg

Plexin A1 (Sema Domain) - PX1475 from ECM Biosciences

Category Peptide
Prices $55.00
Sizes 50 μg

Plexin-A1 - RPC141015 from Biomatik

Category Protein
Prices $299.20, $352.00, $550.00, $687.50, $997.50, $1,507.50
Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg
Source E.coli
Species Human

Plexin-A1 - RPC141016 from Biomatik

Category Protein
Prices $299.20, $352.00, $550.00, $687.50, $997.50, $1,507.50
Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg
Source Yeast
Species Human

Plexin-A1 - RPC141017 from Biomatik

Category Protein
Prices $299.20, $352.00, $550.00, $687.50, $997.50, $1,507.50
Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg
Source E.coli
Species Human

Plexin A1 Protein (Recombinant) - abx167059 from Abbexa

Category Protein
Source Human
Species Human

Plexin A1 - TP322057 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
Plexin A1

Plexin-A1, Recombinant Protein - MBS1265363 from MyBioSource

Category Protein
Prices $195.00, $465.00, $815.00, $1,290.00
Sizes 50 µg, 200 µg, 500 µg, 1 mg
Source E Coli

Plexin-A1, Recombinant Protein - MBS1265228 from MyBioSource

Category Protein
Prices $190.00, $460.00, $750.00, $1,180.00
Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 1 mg (E-Coli)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
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