Gene Symbol | VPS37A |
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Entrez Gene | 137492 |
Alt Symbol | HCRP1, PQBP2, SPG53 |
Species | Human |
Gene Type | protein-coding |
Description | vacuolar protein sorting 37 homolog A (S. cerevisiae) |
Other Description | ESCRT-I complex subunit VPS37A|hepatocellular carcinoma-related protein 1|polyglutamine binding protein 2|vacuolar protein sorting-associated protein 37A |
Swissprots | Q6NW27 Q96DL9 Q336D5 Q8TBL7 Q8NEZ2 Q8N3D7 |
Accessions | EAW63817 EAW63818 EAW63819 Q8NEZ2 AF547097 AAQ12067 AK057204 BAB71381 AK090607 AK124607 BAG54057 AY033079 AAK54349 BC022363 AAH22363 BC067754 AAH67754 HQ447456 ADQ31942 XM_005273400 XP_005273457 XM_005273401 XP_005273458 XM_006716286 XP_006716349 NM_001145152 NP_001138624 NM_152415 NP_689628 |
Function | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. {ECO:0000269|PubMed:15240819}. |
Subcellular Location | Late endosome membrane; Peripheral membrane protein. Nucleus. |
Tissue Specificity | Widely expressed. Examined tissues include heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. More abundant in liver. Strongly decreased or undetected in hepatomas. {ECO:0000269|PubMed:14623289, ECO:0000269|PubMed:22717650}. |
Top Pathways | Endocytosis |
Human VPS37A full length protein - ab165405 from Abcam
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VPS37A Antibody Blocking Peptide - LS-E19092 from LifeSpan Bioscience
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Recombinant Human VPS37A Protein - H00137492-P01 from Novus Biologicals
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VPS37A-Antibody-C-term-Blocking-Peptide - BP16960b from Abgent, a WuXi AppTec company
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VPS37A Blocking Peptide - 33R-8941 from Fitzgerald
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VPS37A - H00137492-P01-10 from Acris Antibodies
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VPS37A - H00137492-P01-25 from Acris Antibodies
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VPS37A fusion protein - Ag19108 from Proteintech Group
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VPS37A fusion protein - Ag2453 from Proteintech Group
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Recombinant Human VPS37A, His-tagged - VPS37A-3680H from Creative Biomart
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Recombinant Hepatocellular Carcinoma Related Protein 1 (HCRP1) - RPN237Hu01 from Uscn Life Science Inc.
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Recombinant Hepatocellular Carcinoma Related Protein 1 (HCRP1) - RPN237Hu01 from Cloud-clone
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Recombinant Human Vacuolar protein sorting-associated protein 37A(VPS37A) - CSB-YP818779HU CSB-EP818779HU CSB-BP818779HU CSB-MP818779HU from Cusabio
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VPS37A Protein - abx164557 from Abbexa
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Vacuolar protein sorting-associated protein 37A(VPS37A) , Recombinant Protein - MBS1370763 from MyBioSource
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VPS37A Recombinant Protein Antigen - NBP1-81994PEP from Novus Biologicals
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VPS37A Recombinant Protein Antigen - NBP1-83528PEP from Novus Biologicals
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VPS37A Peptide, Human - M34GP17318H from Creative Peptides
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VPS37A Recombinant Protein (OPCD03823) - OPCD03823 from Aviva Systems Biology
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Hepatocellular Carcinoma Related Protein 1, Recombinant Protein - MBS2033183 from MyBioSource
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Recombinant Human VPS37A protein, His & T7-tagged - VPS37A-1443H from Creative Biomart
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