VPS37A

Gene Symbol VPS37A
Entrez Gene 137492
Alt Symbol HCRP1, PQBP2, SPG53
Species Human
Gene Type protein-coding
Description vacuolar protein sorting 37 homolog A (S. cerevisiae)
Other Description ESCRT-I complex subunit VPS37A|hepatocellular carcinoma-related protein 1|polyglutamine binding protein 2|vacuolar protein sorting-associated protein 37A
Swissprots Q6NW27 Q96DL9 Q336D5 Q8TBL7 Q8NEZ2 Q8N3D7
Accessions EAW63817 EAW63818 EAW63819 Q8NEZ2 AF547097 AAQ12067 AK057204 BAB71381 AK090607 AK124607 BAG54057 AY033079 AAK54349 BC022363 AAH22363 BC067754 AAH67754 HQ447456 ADQ31942 XM_005273400 XP_005273457 XM_005273401 XP_005273458 XM_006716286 XP_006716349 NM_001145152 NP_001138624 NM_152415 NP_689628
Function Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. {ECO:0000269|PubMed:15240819}.
Subcellular Location Late endosome membrane; Peripheral membrane protein. Nucleus.
Tissue Specificity Widely expressed. Examined tissues include heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. More abundant in liver. Strongly decreased or undetected in hepatomas. {ECO:0000269|PubMed:14623289, ECO:0000269|PubMed:22717650}.
Top Pathways Endocytosis

VPS37 (E-16) - sc-50190 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VPS37 (E-16): sc-50190. Western blot analysis of VPS37 expression in mouse liver (A) and rat liver (B) tissue extracts.

VPS37 (S-18) - sc-50192 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VPS37 (S-18): sc-50192. Western blot analysis of VPS37 expression in MCF7 nuclear extract.

VPS37 (T-20) - sc-50193 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VPS37 (T-20): sc-50193. Western blot analysis of VPS37 expression in human liver (A), mouse liver (B) and rat liver (C) tissue extracts.

VPS37A (G-3) - sc-376978 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VPS37A (G-3): sc-376978. Western blot analysis of VPS37A expression in MCF7 nuclear extract.

VPS37A (H-300) - sc-98470 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
VPS37A (H-300): sc-98470. Western blot analysis of VPS37A expression in A549 whole cell lysate.

Anti-VPS37A antibody - ab177055 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical staining of formalin-fixed paraffin-embedded human kidney tissue labeling VPS37A with ab177055 at 1/100 showing cytoplasmic staining.

Anti-VPS37A antibody - ab85843 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-VPS37A antibody (ab85843) at 1 µg/ml + MCF7 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-VPS37A Antibody - LS-C294474 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-VPS37A Antibody (Biotin) - LS-C297397 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-VPS37A Antibody (FITC) - LS-C305000 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-VPS37A Antibody (N-Terminus) - LS-C102498 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
VPS37A antibody LS-C102498 Western blot of MCF7 cell lysate.

Anti-VPS37A Antibody - LS-C331497 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of Liver cell lysate using HCRP1 antibody.

VPS37A Antibody - NBP1-83528 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VPS37A Antibody - NBP1-03431 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VPS37A Antibody - NBP1-81994 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-VPS37A antibody produced in rabbit - HPA024781 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-VPS37A: <B>Cat. No. HPA024781</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in tubular cells.

Anti-VPS37A antibody produced in rabbit - HPA024705 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-VPS37A: <B>Cat. No. HPA024705</B>: Immunohistochemical staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.

VPS37A antibody - N-terminal region (ARP52954_P050) - ARP52954_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VPS37A antibody - 70R-21271 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

VPS37A antibody - 70R-2831 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

HCRP1 Polyclonal Antibody - A1505 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of Liver cell lysate using HCRP1 antibody.

VPS37A Antibody - abx037035 from Abbexa

Host Rabbit
Clonality Polyclonal

VPS37A antibody - 11870-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Human  liver were subjected to SDS PAGE followed by western blot with 11870-1-AP(VPS37A Antibody) at dilution of 1:600

Anti-HCRP1, Polyclonal Antibody - 25-A1505 from ARP American Research Products

Prices $299.00, $449.00
Sizes 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

Anti-Hepatocellular Carcinoma Related Protein 1 (HCRP1) - 20-5633 from ARP American Research Products

Prices $389.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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