VPS37A

Gene Symbol VPS37A
Entrez Gene 137492
Alt Symbol HCRP1, PQBP2, SPG53
Species Human
Gene Type protein-coding
Description vacuolar protein sorting 37 homolog A (S. cerevisiae)
Other Description ESCRT-I complex subunit VPS37A|hepatocellular carcinoma-related protein 1|polyglutamine binding protein 2|vacuolar protein sorting-associated protein 37A
Swissprots Q6NW27 Q96DL9 Q336D5 Q8TBL7 Q8NEZ2 Q8N3D7
Accessions EAW63817 EAW63818 EAW63819 Q8NEZ2 AF547097 AAQ12067 AK057204 BAB71381 AK090607 AK124607 BAG54057 AY033079 AAK54349 BC022363 AAH22363 BC067754 AAH67754 HQ447456 ADQ31942 XM_005273400 XP_005273457 XM_005273401 XP_005273458 XM_006716286 XP_006716349 NM_001145152 NP_001138624 NM_152415 NP_689628
Function Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. {ECO:0000269|PubMed:15240819}.
Subcellular Location Late endosome membrane; Peripheral membrane protein. Nucleus.
Tissue Specificity Widely expressed. Examined tissues include heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. More abundant in liver. Strongly decreased or undetected in hepatomas. {ECO:0000269|PubMed:14623289, ECO:0000269|PubMed:22717650}.
Top Pathways Endocytosis

VPS37 CRISPR/Cas9 KO Plasmid (h) - sc-405291 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

VPS37 HDR Plasmid (h) - sc-405291-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VPS37 Double Nickase Plasmid (h) - sc-405291-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VPS37 Double Nickase Plasmid (h2) - sc-405291-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VPS37 CRISPR Activation Plasmid (h) - sc-405291-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

VPS37 CRISPR Activation Plasmid (h2) - sc-405291-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

VPS37 Lentiviral Activation Particles (h) - sc-405291-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VPS37 Lentiviral Activation Particles (h2) - sc-405291-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VPS37 siRNA (h) - sc-61796 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

VPS37 shRNA Plasmid (h) - sc-61796-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

VPS37 shRNA (h) Lentiviral Particles - sc-61796-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU087801 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22721 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22721 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04667 from Sigma-Aldrich

Category miRNA

VPS37A siRNA (Human) - CRJ5198 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

VPS37A - MBS8225232 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human VPS37A (NM_152415.2) - SHH444976 from Creative biogene

Category siRNA
Species Reactivities Human

VPS37A shRNA Plasmid (Human) - CHJ5198 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

VPS37A miRNA 3'UTR clone - MiUTR4H-TG09787 from Creative biogene

Species Reactivities Human
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