Gene Symbol | QTRT1 |
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Entrez Gene | 81890 |
Alt Symbol | FP3235, TGT, TGUT |
Species | Human |
Gene Type | protein-coding |
Description | queuine tRNA-ribosyltransferase 1 |
Other Description | TGT, 43-KD subunit|TGT, catalytic subunit|guanine insertion enzyme|queuine tRNA-ribosyltransferase|tRNA-guanine transglycosylase |
Swissprots | B4DFM7 Q9BXR0 Q9BXQ9 Q96BQ4 |
Accessions | EAW84138 EAW84139 EAW84140 EAW84141 EAW84142 EAW84143 Q9BXR0 AF302783 AAG60033 AF302784 AAG60034 AF302785 AF370379 AAQ15215 AK055216 AK057877 AK225173 AK294166 BAG57488 AK314308 BAG36960 BC015350 AAH15350 CT003728 NM_031209 NP_112486 |
Function | Interacts with QTRTD1 to form an active queuine tRNA- ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1- yl)amino)methyl)-7-deazaguanosine) (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Mitochondrion {ECO:0000250}. Nucleus {ECO:0000250}. Note=Weakly associates with mitochondria, possibly via QTRTD1. {ECO:0000250}. |
QTRT1 (D-7) - sc-398918 from Santa Cruz Biotechnology
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QTRT1 (N-20) - sc-243907 from Santa Cruz Biotechnology
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QTRT1 (S-18) - sc-243908 from Santa Cruz Biotechnology
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Anti-QTRT1 antibody - ab85424 from Abcam
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Anti-QTRT1 antibody - ab68051 from Abcam
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Anti-QTRT1 antibody - ab187891 from Abcam
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Anti-QTRT1 antibody - C-terminal - ab173601 from Abcam
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Anti-QTRT1 antibody - C-terminal - ab202323 from Abcam
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Anti-QTRT1 Antibody (aa345-371, AP) - LS-C267650 from LifeSpan Bioscience
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Anti-QTRT1 Antibody (aa345-371, APC) - LS-C267651 from LifeSpan Bioscience
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Anti-QTRT1 Antibody (aa345-371, PE) - LS-C267655 from LifeSpan Bioscience
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Anti-QTRT1 Antibody (aa345-371, FITC) - LS-C267653 from LifeSpan Bioscience
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Anti-QTRT1 Antibody (aa345-371, Azide-free, HRP) - LS-C267654 from LifeSpan Bioscience
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Anti-QTRT1 Antibody (aa344-371) - LS-C324455 from LifeSpan Bioscience
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Anti-QTRT1 Antibody (aa45-94) - LS-C81331 from LifeSpan Bioscience
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Anti-QTRT1 Antibody (aa252-301) - LS-C102327 from LifeSpan Bioscience
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Anti-QTRT1 Antibody (aa345-371) - LS-C158779 from LifeSpan Bioscience
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Anti-QTRT1 Antibody IHC-plus⢠- LS-B10514 from LifeSpan Bioscience
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Anti-QTRT1 Antibody (aa303-337) - LS-C344412 from LifeSpan Bioscience
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Anti-QTRT1 Antibody (aa345-371, Biotin) - LS-C267652 from LifeSpan Bioscience
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QTRT1 Antibody - NBP2-20030 from Novus Biologicals
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QTRT1 Antibody - H00081890-B01 from Novus Biologicals
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QTRT1 Antibody - H00081890-B01P from Novus Biologicals
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Anti-QTRT1 antibody produced in rabbit - HPA048651 from Sigma-Aldrich
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Anti-QTRT1 antibody produced in rabbit - HPA049440 from Sigma-Aldrich
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