Gene Symbol | QTRT1 |
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Entrez Gene | 81890 |
Alt Symbol | FP3235, TGT, TGUT |
Species | Human |
Gene Type | protein-coding |
Description | queuine tRNA-ribosyltransferase 1 |
Other Description | TGT, 43-KD subunit|TGT, catalytic subunit|guanine insertion enzyme|queuine tRNA-ribosyltransferase|tRNA-guanine transglycosylase |
Swissprots | B4DFM7 Q9BXR0 Q9BXQ9 Q96BQ4 |
Accessions | EAW84138 EAW84139 EAW84140 EAW84141 EAW84142 EAW84143 Q9BXR0 AF302783 AAG60033 AF302784 AAG60034 AF302785 AF370379 AAQ15215 AK055216 AK057877 AK225173 AK294166 BAG57488 AK314308 BAG36960 BC015350 AAH15350 CT003728 NM_031209 NP_112486 |
Function | Interacts with QTRTD1 to form an active queuine tRNA- ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1- yl)amino)methyl)-7-deazaguanosine) (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Mitochondrion {ECO:0000250}. Nucleus {ECO:0000250}. Note=Weakly associates with mitochondria, possibly via QTRTD1. {ECO:0000250}. |
Ubiquitin Specific Peptidase 14 (USP14), Human, ELISA Kit - SEF134Hu from ARP American Research Products
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ELISA Kit for Ubiquitin Specific Peptidase 14 (USP14) - SEF134Hu from Cloud-clone
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Human QTRT1 ELISA Kit - E100218 from Biobool
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Human Ubiquitin carboxyl-terminal hydrolase 14 (USP14) ELISA Kit - AE12035HU from ARP American Research Products
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TGT (tRNA-Guanine Transglycosylase), ELISA Kit - MBS7606255 from MyBioSource
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QTRT1 ELISA Kit (Human) (OKWB00222) - OKWB00222 from Aviva Systems Biology
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Human QTRT1 ELISA Kit (Sandwich ELISA) - LS-F32014 from LifeSpan Bioscience
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