Gene Symbol | QTRT1 |
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Entrez Gene | 81890 |
Alt Symbol | FP3235, TGT, TGUT |
Species | Human |
Gene Type | protein-coding |
Description | queuine tRNA-ribosyltransferase 1 |
Other Description | TGT, 43-KD subunit|TGT, catalytic subunit|guanine insertion enzyme|queuine tRNA-ribosyltransferase|tRNA-guanine transglycosylase |
Swissprots | B4DFM7 Q9BXR0 Q9BXQ9 Q96BQ4 |
Accessions | EAW84138 EAW84139 EAW84140 EAW84141 EAW84142 EAW84143 Q9BXR0 AF302783 AAG60033 AF302784 AAG60034 AF302785 AF370379 AAQ15215 AK055216 AK057877 AK225173 AK294166 BAG57488 AK314308 BAG36960 BC015350 AAH15350 CT003728 NM_031209 NP_112486 |
Function | Interacts with QTRTD1 to form an active queuine tRNA- ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1- yl)amino)methyl)-7-deazaguanosine) (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Mitochondrion {ECO:0000250}. Nucleus {ECO:0000250}. Note=Weakly associates with mitochondria, possibly via QTRTD1. {ECO:0000250}. |
Human QTRT1 full length protein - ab164380 from Abcam
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Human QTRT1 full length protein - ab202188 from Abcam
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QTRT1 Antibody Blocking Peptide - LS-E5162 from LifeSpan Bioscience
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QTRT1 Antibody Blocking Peptide - LS-E17706 from LifeSpan Bioscience
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QTRT1 Antibody Blocking Peptide - LS-E17705 from LifeSpan Bioscience
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QTRT1 Recombinant Protein - H00081890-P01 from Novus Biologicals
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QTRT1-Antibody-C-term-Blocking-Peptide - BP17592b from Abgent, a WuXi AppTec company
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QTRT1 Blocking Peptide - 33R-3000 from Fitzgerald
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QTRT1 Blocking Peptide - 33R-4290 from Fitzgerald
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QTRT1 protein - 80R-4237 from Fitzgerald
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QTRT1 (1-403, His-tag) - AR51919PU-N from Acris Antibodies
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QTRT1 (1-403, His-tag) - AR51919PU-S from Acris Antibodies
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QTRT1 - H00081890-P01-10 from Acris Antibodies
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QTRT1 - H00081890-P01-25 from Acris Antibodies
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QTRT1 fusion protein - ag3010 from Proteintech Group
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USP14 Human - PRPS-023 from NeoScientific
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Recombinant Human QTRT1, His-tagged - QTRT1-79H from Creative Biomart
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Recombinant Ubiquitin Specific Peptidase 14 (USP14) - RPF134Hu01 from Cloud-clone
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Recombinant Queuine tRNA-ribosyltransferase(tgt) - CSB-YP889327XBL CSB-EP889327XBL CSB-BP889327XBL CSB-MP889327XBL from Cusabio
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Recombinant Human Queuine tRNA-ribosyltransferase(QTRT1) - CSB-YP887150HU CSB-EP887150HU CSB-BP887150HU CSB-MP887150HU from Cusabio
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Recombinant Queuine tRNA-ribosyltransferase(tgt) - CSB-YP859245SMT CSB-EP859245SMT CSB-BP859245SMT CSB-MP859245SMT from Cusabio
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Recombinant Queuine tRNA-ribosyltransferase(tgt) - CSB-YP855641CMB CSB-EP855641CMB CSB-BP855641CMB CSB-MP855641CMB from Cusabio
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Recombinant Queuine tRNA-ribosyltransferase(tgt) - CSB-YP852453SWW CSB-EP852453SWW CSB-BP852453SWW CSB-MP852453SWW from Cusabio
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Recombinant Queuine tRNA-ribosyltransferase(tgt) - CSB-YP849349YAS CSB-EP849349YAS CSB-BP849349YAS CSB-MP849349YAS from Cusabio
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Recombinant Queuine tRNA-ribosyltransferase(tgt) - CSB-YP814989SMH CSB-EP814989SMH CSB-BP814989SMH CSB-MP814989SMH from Cusabio
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