HTR2C

Gene Symbol HTR2C
Entrez Gene 3358
Alt Symbol 5-HT1C, 5-HT2C, 5-HTR2C, 5HTR2C, HTR1C
Species Human
Gene Type protein-coding
Description 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
Other Description 5-hydroxytryptamine receptor 1C|5-hydroxytryptamine receptor 2C|serotonin 5-HT-1C receptor|serotonin 5-HT-2C receptor
Swissprots Q9NP28 Q5VUF8 P28335 B1AMW4
Accessions AAC71658 ACE96318 ACE96323 ACE96328 CAB59978 EAX02623 EAX02624 P28335 AF208053 AAF35842 AF498983 AAM21130 AK295753 BAG58583 AK308766 AY114104 AAM78371 BC028688 BC095543 AAH95543 BX648587 FJ200493 ACO54890 M81778 AAA60317 U49516 AAB40898 NM_000868 NP_000859 NM_001256760 NP_001243689 NM_001256761 NP_001243690
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1- 2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release o
Subcellular Location Cell membrane {ECO:0000269|PubMed:12970106, ECO:0000269|PubMed:18703043, ECO:0000269|PubMed:19057895, ECO:0000269|PubMed:7895773}; Multi-pass membrane protein {ECO:0000269|PubMed:12970106, ECO:0000269|PubMed:18703043, ECO:0000269|PubMed:19057895, ECO:0000269|PubMed:7895773}.
Tissue Specificity Detected in brain. {ECO:0000269|PubMed:8812491}.
Top Pathways Gap junction, Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction

Rat HTR2C / 5-HT2C Receptor ELISA Kit (Sandwich ELISA) - LS-F7038 from LifeSpan Bioscience

Category ELISA Kit
Prices $780.00
Sizes 1 plate
Sensitivity 0.115 ng/ml
Range 0.313-20 ng/ml

5-Hydroxytryptamine Receptor 2C, ELISA Kit - MBS083712 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2C, ELISA Kit - MBS050512 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2C, ELISA Kit - MBS108639 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2C, ELISA Kit - MBS054434 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2C, ELISA Kit - MBS084913 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2C, ELISA Kit - MBS084187 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2C, ELISA Kit - MBS097253 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2C (HTR2C), ELISA Kit - MBS2024647 from MyBioSource

Category ELISA Kit
Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.115ng/mL.
Range 0.313-20ng/mL

ELISA Kit for 5-Hydroxytryptamine Receptor 2C (HTR2C) - SED488Ra from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.115ng/mL.
Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human HTR2C ELISA Kit - E042084 from Biobool

Category ELISA Kit

anti-Serotonin receptor 2C / HTR2C antibody - ARG63766 from Arigo Biolaboratories

Category ELISA Kit

5-hydroxytryptamine receptor 2C, ELISA Kit - MBS283871 from MyBioSource

Category ELISA Kit
Prices $465.00, $790.00, $3,500.00, $6,655.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2C (HTR2C), ELISA Kit - MBS9372224 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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