CATSPER2

Gene Symbol CATSPER2
Entrez Gene 117155
Alt Symbol -
Species Human
Gene Type protein-coding
Description cation channel, sperm associated 2
Other Description cation channel sperm-associated protein 2|sperm ion channel
Swissprots Q96P55 Q96P54 Q8NHT9 Q96P56
Accessions EAW50798 EAW50801 EAW50802 Q96P56 AF411817 AAL26490 AF411818 AAL26491 AF411819 AAL26492 AK093318 AK122607 BAG53620 AW135409 BC028728 AAH28728 BC064387 AAH64387 BM998110 BX648099 DQ655952 HQ448354 ADQ32834 XM_011521204 XP_011519506 NM_001282309 NP_001269238 NM_001282310 NP_001269239 NM_054020 NP_473361 NM_172095 NP_742093 NR_110319 NM_172097
Function Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH. {ECO:0000269|PubMed:21412338, ECO:0000269|PubMed:21412339}.
Subcellular Location Cell projection, cilium, flagellum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Specifically located in the principal piece of sperm tail.
Tissue Specificity Testis-specific. {ECO:0000269|PubMed:11675491, ECO:0000269|PubMed:17347248}.

CatSper2 (H-60) - sc-98539 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CatSper2 (H-60): sc-98539. Western blot analysis of CatSper2 expression in 293T (A), Hep G2 (B), MCF7 (C) and Y79 (D) whole cell lysates and mouse testis tissue extract (E).

CatSper2 (L-17) - sc-83119 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CatSper2 (T-17) - sc-83122 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CatSper2 (T-17): sc-83122. Western blot analysis of CatSper2 expression in mouse liver (A) and mouse placenta (B) tissue extracts.

Anti-CatSper2 antibody - ab150890 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Paraffin-embedded Human soft tissue labeling CatSper2 with ab150890 at 1/50 dilution.

Anti-CatSper2 antibody - ab49341 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CatSper2 antibody (ab49341) at 1.25 µg/ml + Jurkat cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-CatSper2 antibody - ab66642 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CatSper2 antibody (ab66642) at 1.25 µg/mlLane 1 : Molecular weight markersLane 2 : HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-CATSPER2 Antibody (aa31-80) - LS-C31616 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
CATSPER2 antibody LS-C31616 was used in IHC to stain formalin-fixed, paraffin-embedded human brain.

Anti-CATSPER2 Antibody (aa472-500) - LS-C320017 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CATSPER2 Antibody (C-Terminus) - LS-C31685 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: HepG2 Cell Lysate

Anti-CATSPER2 Antibody (aa31-80) - LS-C115945 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CATSPER2 antibody LS-C115945 Western blot of Placenta lysate.

Anti-CATSPER2 Antibody (aa472-500) - LS-C159272 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CATSPER2 Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The CATSPER2 antibody detected the CATSPER2 protein (arrow).

Anti-CATSPER2 Antibody (aa472-500, AP) - LS-C233397 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CATSPER2 Antibody (aa472-500, Biotin) - LS-C233398 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CATSPER2 Antibody (aa472-500, PE) - LS-C233404 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CATSPER2 Antibody (aa472-500, Azide-free, HRP) - LS-C249578 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CATSPER2 Antibody (aa472-500, APC) - LS-C233399 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CATSPER2 Antibody (aa472-500, FITC) - LS-C233400 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

CatSper2 Antibody - NBP2-14439 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CatSper2 Antibody [NBP2-14439] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)<br/>Lane 5: Human liver tissue<br/>Lane 6: Human tonsil tissue

CatSper2 Antibody - NBP1-46506 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CATSPER2 Polyclonal Antibody - bs-10473R from Bioss

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CATSPER2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-10473R-A350 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CATSPER2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-10473R-A488 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CATSPER2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-10473R-A555 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CATSPER2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-10473R-A647 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CATSPER2 Polyclonal Antibody, Cy3 Conjugated - bs-10473R-Cy3 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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