SUMO3

Gene Symbol	SUMO3
Entrez Gene	6612
Alt Symbol	SMT3A, SMT3H1, SUMO-3, Smt3B
Species	Human
Gene Type	protein-coding
Description	small ubiquitin-like modifier 3
Other Description	SMT3 suppressor of mif two 3 homolog 1|SMT3 suppressor of mif two 3 homolog 3|small ubiquitin-related modifier 3|ubiquitin-like protein SMT3B
Swissprots	P55854 Q6FGD4 B4DUW4 Q9BWR4 Q53HI9 B2R5X4
Accessions	EAX09390 EAX09391 EAX09392 EAX09393 P55854 AK222591 BAD96311 AK300822 BAG62476 AK312350 BAG35271 BC000036 AAH00036 BC008420 AAH08420 BT007008 AAP35654 CR542173 CAG46970 CR542188 CAG46985 X99584 CAA67896 NM_001286416 NP_001273345 NM_006936 NP_008867
Function	Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4 (PubMed:11451954, PubMed:18538659, PubMed:21965678). Plays a role in the regulation of sumoylation status of SETX (PubMed:24105744). {ECO:0000269|PubMed:11451954, ECO:0000269|PubMed:18538659, ECO:0000269|PubMed:21965678}.
Subcellular Location	Cytoplasm. Nucleus. Nucleus, PML body {ECO:0000250}.
Tissue Specificity	Expressed predominantly in liver. {ECO:0000269|PubMed:15487983}.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SUMO3-Over-expression-Lysate - LY11068a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

SUMO3 293T Cell Transient Overexpression Lysate(Denatured) - H00006612-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

SUMO3 overexpression lysate - LY402068 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

SUMO3 293 Cell Lysate - 401832 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

SUMO3 Overexpression Lysate (Denatured) - H00006612-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

SUMO3 Overexpression Lysate (Native) - NBL1-16613 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SUMO3 Over-expression Lysate Product - GWB-9434BF from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human SUMO3 Knockdown Stable Cell Line - CSC-DC015406 from Creative biogene Category Cell Line Species Human

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