SUMO3

Gene Symbol SUMO3
Entrez Gene 6612
Alt Symbol SMT3A, SMT3H1, SUMO-3, Smt3B
Species Human
Gene Type protein-coding
Description small ubiquitin-like modifier 3
Other Description SMT3 suppressor of mif two 3 homolog 1|SMT3 suppressor of mif two 3 homolog 3|small ubiquitin-related modifier 3|ubiquitin-like protein SMT3B
Swissprots P55854 Q6FGD4 B4DUW4 Q9BWR4 Q53HI9 B2R5X4
Accessions EAX09390 EAX09391 EAX09392 EAX09393 P55854 AK222591 BAD96311 AK300822 BAG62476 AK312350 BAG35271 BC000036 AAH00036 BC008420 AAH08420 BT007008 AAP35654 CR542173 CAG46970 CR542188 CAG46985 X99584 CAA67896 NM_001286416 NP_001273345 NM_006936 NP_008867
Function Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4 (PubMed:11451954, PubMed:18538659, PubMed:21965678). Plays a role in the regulation of sumoylation status of SETX (PubMed:24105744). {ECO:0000269|PubMed:11451954, ECO:0000269|PubMed:18538659, ECO:0000269|PubMed:21965678}.
Subcellular Location Cytoplasm. Nucleus. Nucleus, PML body {ECO:0000250}.
Tissue Specificity Expressed predominantly in liver. {ECO:0000269|PubMed:15487983}.
Top Pathways RNA transport

Active human Sumo 3 full length protein - ab189693 from Abcam

Category Protein
Prices $342.00
Sizes 500 µl
Source E. coli
Species Human

Active Sumo 3 full length protein - ab3802 from Abcam

Category Protein
Prices $239.00
Sizes 100 µg
Source E. coli

Human Sumo 3 full length protein - ab140414 from Abcam

Category Protein
Source E. coli
Species Human
SDS-PAGE analysis of ab140414.

Human Sumo 3 full length protein - ab131972 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE stained with Coomassie Blue, showing ab131972 at approximately 36.96 kDa.

Human Sumo 3 full length protein - ab152093 from Abcam

Category Protein
Source HEK 293 cells
Species Human

Human Sumo 3 full length protein - ab99866 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE showing ab99866 (3µg). Note: Molecular weight on SDS-PAGE will appear higher.

Human Sumo 3 full length protein - ab189690 from Abcam

Category Protein
Source E. coli
Species Human

Human Sumo 3 full length protein - ab189730 from Abcam

Category Protein
Source E. coli
Species Human

Human Sumo 3 full length protein - ab190018 from Abcam

Category Protein
Source E. coli
Species Human

Human Sumo 3 full length protein - ab190038 from Abcam

Category Protein
Source E. coli
Species Human

Human Sumo 3 full length protein - ab168888 from Abcam

Category Protein
Source E. coli
Species Human

Human Sumo 3 protein fragment - ab159550 from Abcam

Category Protein
Source Wheat germ
Species Human
ab159550 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human Sumo 3 protein fragment - ab157052 from Abcam

Category Protein
Source E. coli
Species Human

SUMO3 Antibody Blocking Peptide - LS-E30928 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

SUMO3 Antibody Blocking Peptide - LS-E16723 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SUMO3 Antibody Blocking Peptide - LS-E21311 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SUMO3 Recombinant Protein - H00006612-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

SUMO3 Partial Recombinant Protein - H00006612-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

SUMO3 Blocking Peptide - NBP1-77164PEP from Novus Biologicals

Category Peptide
Prices $129.00
Sizes 50 µg
Species Human

Recombinant Human SUMO3 Protein - NBP1-99840 from Novus Biologicals

Category Protein
Prices $185.00
Sizes 100 µg
Source E. coli
Species Human

Recombinant Human SUMO3 Protein - NBP1-49438 from Novus Biologicals

Category Protein
Prices $269.00, $729.00
Sizes 100 µg, 500 µg
Source E.coli
Species Human

SUMO3 Peptide - P0288 from Novus Biologicals

Category Peptide
Species Human

SUMO23-Antibody-C-term-Blocking-Peptide - BP1224a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

SUMO23-Antibody-Center-Blocking-Peptide - BP1223d from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg
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