Gene Symbol | DENND1A |
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Entrez Gene | 57706 |
Alt Symbol | FAM31A, KIAA1608 |
Species | Human |
Gene Type | protein-coding |
Description | DENN/MADD domain containing 1A |
Other Description | DENN domain-containing protein 1A|connecdenn 1 |
Swissprots | Q6PJZ5 B7Z669 D3PFD3 Q9H796 Q8TEH3 B7Z3C8 Q5VWF0 A8MZA3 B1AM80 Q05C88 Q8IVD6 |
Accessions | EAW87569 EAW87570 EAW87571 EAW87572 EAW87573 EAW87574 EAW87575 Q8TEH3 AB046828 BAB13434 AK024782 BAB15002 AK074151 BAB84977 AK225104 AK295710 BAH12164 AK299867 BAH13155 BC009616 AAH09616 BC028061 AAH28061 BC039703 AAH39703 BK006958 DAA12500 JF432807 ADZ16024 XM_005252109 XP_005252166 XM_005252111 XP_005252168 XM_005252113 XP_005252170 XM_006717195 XP_006717258 XM_011518882 XP_011517184 XM_011518883 XP_011517185 XM_011518884 XP_011517186 XM_011518885 XP_011517187 XM_011518886 XP_011517188 XM_011518887 XP_011517189 XR_929829 XR_929830 NM_020946 NP_065997 NM_024820 NP_079096 |
Function | Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles. {ECO:0000269|PubMed:20154091, ECO:0000269|PubMed:20937701}. |
Subcellular Location | Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000269|PubMed:20937701}; Peripheral membrane protein {ECO:0000269|PubMed:20937701}. Cell junction, synapse, presynaptic cell membrane {ECO:0000269|PubMed:20937701}. |
DENND1A (N-14) - sc-164162 from Santa Cruz Biotechnology
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Anti-DENND1A antibody - ab103224 from Abcam
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Anti-DENND1A antibody - ab125347 from Abcam
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Anti-DENND1A antibody - ab103987 from Abcam
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Anti-DENND1A Antibody (aa583-613) - LS-C320806 from LifeSpan Bioscience
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Anti-DENND1A Antibody (aa143-192) - LS-C110911 from LifeSpan Bioscience
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Anti-DENND1A Antibody (aa576-605) - LS-C167356 from LifeSpan Bioscience
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Anti-DENND1A Antibody (aa576-605, APC) - LS-C256018 from LifeSpan Bioscience
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Anti-DENND1A Antibody (aa576-605, Biotin) - LS-C256019 from LifeSpan Bioscience
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Anti-DENND1A Antibody (aa576-605, AP) - LS-C256017 from LifeSpan Bioscience
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Anti-DENND1A Antibody (aa585-634) - LS-C146434 from LifeSpan Bioscience
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Anti-DENND1A Antibody (aa576-605, FITC) - LS-C256020 from LifeSpan Bioscience
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Anti-DENND1A Antibody (aa576-605, Azide-free, HRP) - LS-C256021 from LifeSpan Bioscience
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Anti-DENND1A Antibody (aa576-605, PE) - LS-C256022 from LifeSpan Bioscience
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DENND1A Antibody - NBP1-55325 from Novus Biologicals
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DENND1A Antibody - NBP1-84742 from Novus Biologicals
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Anti-DENND1A, (N-terminal) antibody produced in rabbit - SAB2106125 from Sigma-Aldrich
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ANTI-DEN1A(C-TERMINAL) antibody produced in rabbit - SAB1306554 from Sigma-Aldrich
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Anti-DENND1A antibody produced in rabbit - HPA020481 from Sigma-Aldrich
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DENND1A antibody - N-terminal region (ARP57501_P050) - ARP57501_P050 from Aviva Systems Biology
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DEN1A-Antibody-C-term - AP9919b from Abgent, a WuXi AppTec company
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DENND1A antibody, N-term - GTX44900 from GeneTex
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DENND1A Antibody - C-terminal region (OAAB06516) - OAAB06516 from Aviva Systems Biology
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DENND1A antibody - 70R-3137 from Fitzgerald
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Anti -DEN1A, CT (DENND1A, FAM31A, KIAA1608, DENN domain-containing protein 1A, Connecdenn1, Protein FAM31A) - 034580 from USBiological Life Science
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