Gene Symbol | TAC4 |
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Entrez Gene | 255061 |
Alt Symbol | EK, HK-1, HK1, PPT-C |
Species | Human |
Gene Type | protein-coding |
Description | tachykinin 4 (hemokinin) |
Other Description | endokinin|preprotachykinin-C|tachykinin-4 |
Swissprots | Q86UU8 Q6ECK8 Q8IWZ7 Q86UU6 Q2M2P1 Q86UU7 Q86UU9 |
Accessions | EAW94657 Q86UU9 AF515828 AAP30874 AF515829 AAP30875 AF515830 AAP30876 AF515831 AAP30877 AF521560 AAN77128 AY471574 AAS46596 BC100840 AAI00841 BC100841 BC100842 AAI00843 BC100843 AAI00844 BC111857 BC111858 NM_001077503 NP_001070971 NM_001077504 NP_001070972 NM_001077505 NP_001070973 NM_001077506 NP_001070974 NM_170685 NP_733786 |
Function | Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin- C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility. {ECO:0000269|PubMed:12716968, ECO:0000269|PubMed:17101218, ECO:0000269|PubMed:17437961, ECO:0000269|PubMed:17655832}. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Expressed at low levels in the uterus of both pregnant and non-pregnant women. Isoform 1 is found only in the adrenal gland and fetal liver. Isoform 2 is found in heart, liver, bone marrow, prostate, adrenal gland and testis. Isoform 3 and isoform 4 are expressed predominantly in adrenal gland and placenta. {ECO:0000269|PubMed:12716968, ECO:0000269|PubMed:12788812}. |
EK (Eepidermal Keratin), Human, ELISA Kit - E-EL-H1083 from ARP American Research Products
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Eepidermal Keratin, EK, Rabbit, ELISA Kit - E-EL-RB0412 from ARP American Research Products
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Eepidermal Keratin, EK, Chicken, ELISA Kit - E-EL-Ch0029 from ARP American Research Products
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Eepidermal Keratin, EK, Porcine, ELISA Kit - E-EL-P0911 from ARP American Research Products
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Eepidermal Keratin, EK, Sheep, ELISA Kit - E-EL-S0663 from ARP American Research Products
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Eepidermal Keratin, EK, Guinea Pig, ELISA Kit - E-EL-GP1220 from ARP American Research Products
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Eepidermal Keratin, EK, Monkey, ELISA Kit - E-EL-MK0184 from ARP American Research Products
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Human EK ELISA Kit - HE0143 from NeoScientific
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Anserine EK ELISA Kit - AE0143 from NeoScientific
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tachykinin 4 (hemokinin) , ELISA Kit - MBS2602776 from MyBioSource
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Tachykinin 4 (TAC4), ELISA Kit - MBS9311705 from MyBioSource
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Human EK (Eepidermal Keratin) ELISA Kit - E-EL-H1083 from Elabscience
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Human EK (Eepidermal Keratin) ELISA Kit - E-EL-H1083 from Iwai North America Inc.
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EK - EKH5974 from Nordic BioSite
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Human EK ELISA Kit - E013403 from Biobool
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Human TAC4 ELISA Kit - E037386 from Biobool
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Human EK ELISA Kit - EHE0143 from ABclonal
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