TAC4

Gene Symbol TAC4
Entrez Gene 255061
Alt Symbol EK, HK-1, HK1, PPT-C
Species Human
Gene Type protein-coding
Description tachykinin 4 (hemokinin)
Other Description endokinin|preprotachykinin-C|tachykinin-4
Swissprots Q86UU8 Q6ECK8 Q8IWZ7 Q86UU6 Q2M2P1 Q86UU7 Q86UU9
Accessions EAW94657 Q86UU9 AF515828 AAP30874 AF515829 AAP30875 AF515830 AAP30876 AF515831 AAP30877 AF521560 AAN77128 AY471574 AAS46596 BC100840 AAI00841 BC100841 BC100842 AAI00843 BC100843 AAI00844 BC111857 BC111858 NM_001077503 NP_001070971 NM_001077504 NP_001070972 NM_001077505 NP_001070973 NM_001077506 NP_001070974 NM_170685 NP_733786
Function Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin- C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility. {ECO:0000269|PubMed:12716968, ECO:0000269|PubMed:17101218, ECO:0000269|PubMed:17437961, ECO:0000269|PubMed:17655832}.
Subcellular Location Secreted {ECO:0000305}.
Tissue Specificity Expressed at low levels in the uterus of both pregnant and non-pregnant women. Isoform 1 is found only in the adrenal gland and fetal liver. Isoform 2 is found in heart, liver, bone marrow, prostate, adrenal gland and testis. Isoform 3 and isoform 4 are expressed predominantly in adrenal gland and placenta. {ECO:0000269|PubMed:12716968, ECO:0000269|PubMed:12788812}.

TAC4 Antibody Blocking Peptide - LS-E1987 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

TAC4-Antibody-C-term-Blocking-peptide - BP12845b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Human HK1 protein - orb80820 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 2 μg, 10 μg
Species Human

TAC4 fusion protein - Ag15702 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human TAC4, GST-tagged - TAC4-3094H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Tachykinin-4(TAC4) - CSB-YP771439HU CSB-EP771439HU CSB-BP771439HU CSB-MP771439HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Tachykinin-4 (TAC4), Recombinant Protein - MBS1392376 from MyBioSource

Category Protein
Prices $770.00, $770.00, $995.00, $995.00, $1,070.00, $1,070.00, $1,525.00, $1,525.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

TAC4 Peptide, Human - M34GP15528H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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