COMMD5

Gene Symbol COMMD5
Entrez Gene 28991
Alt Symbol HCARG, HT002
Species Human
Gene Type protein-coding
Description COMM domain containing 5
Other Description COMM domain-containing protein 5|hypertension-related calcium-regulated gene protein
Swissprots D3DWN7 Q9GZQ3 Q9UHX5 Q9NVN6
Accessions CAD34952 CAE90801 EAW82033 EAW82034 EAW82035 EAW82036 EAW82037 Q9GZQ3 AF113540 AAF14877 AF290195 AAG09915 AK001477 BAA91714 AK023070 BAB14389 AK092477 AW137480 BC002672 AAH02672 BC003055 AAH03055 BC065729 AAH65729 BG705627 BI753202 BM013651 BM924244 BQ680339 BU508224 BU600590 H92104 XR_428379 XR_928321 XR_928322 XR_928323 XR_928324 XR_928325 NM_001081003 NP_001074472 NM_001081004 NP_001074473 NM_001287237 NP_001274166 NM_014066 NP_054785
Function May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity). Down-regulates activation of NF-kappa-B (PubMed:15799966). {ECO:0000250|UniProtKB:Q9ERR2, ECO:0000269|PubMed:15799966, ECO:0000305|PubMed:21778237}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:21778237}. Nucleus {ECO:0000269|PubMed:21778237}.
Tissue Specificity Highly expressed in heart, stomach, jejunum, kidney, liver, and adrenal gland. Expression was generally higher in adult organs than in fetal tissues, particularly in heart, kidney, and liver. {ECO:0000269|PubMed:10918053, ECO:0000269|PubMed:15799966}.

COMMD5 (FL-224) - sc-98314 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
COMMD5 (FL-224): sc-98314. Western blot analysis of COMMD5 expression in Hep G2 whole cell lysate.

COMMD5 (K-14) - sc-87652 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

COMMD5 (N-14) - sc-87653 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-COMD5 antibody - N-terminal - ab176440 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-COMD5 antibody - N-terminal (ab176440) at 1/1000 dilution + Mouse brain total cell extracts

COMMD5 Antibody - NBP2-30531 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: COMMD5 Antibody [NBP2-30531] - Immunohistochemical staining of human testis shows moderate cytoplasmic staining in subset of cells in seminiferus ducts and Leydig cells.

COMMD5 Antibody - NBP2-30916 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: COMMD5 Antibody [NBP2-30916] - Immunohistochemical staining of human esophagus shows strong cytoplasmic positivity in superficial layer of squamous epithelial cells.

Anti-COMMD5 antibody produced in rabbit - HPA046905 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-COMMD5: <B>Cat. No. HPA046905</B>: Immunohistochemical staining of human esophagus shows strong cytoplasmic positivity in superficial layer of squamous epithelial cells.

Anti-COMMD5 (101-115) antibody produced in rabbit - SAB1101760 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-COMMD5 (101-115) (RB): <B>Cat. No. SAB1101760</B>: Immunofluorescence of HUVEC cells using Anti-COMMD5 (101-115) (RB) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-COMMD5 antibody produced in rabbit - HPA046989 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-COMMD5: <B>Cat. No. HPA046989</B>: Immunohistochemical staining of human testis shows moderate cytoplasmic staining in subset of cells in seminiferus ducts and Leydig cells.

Anti -COMMD5 (COMM Domain-containing Protein 5, HCARG, HT002) - 210206 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

COMMD5 Polyclonal Antibody - A4664 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal

COMMD5 antibody - 70R-16508 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

COMMD5 Antibody - abx003517 from Abbexa

Host Rabbit
Clonality Polyclonal

COMMD5 antibody - 10393-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Mouse kidney were subjected to SDS PAGE followed by western blot with 10393-1-AP(COMMD5 Antibody) at dilution of 1:1000

COMMD5 antibody - H00028991-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-COMMD5, Polyclonal Antibody - 25-A4664 from ARP American Research Products

Prices $379.00, $549.00
Sizes 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

COMMD5 antibody - 10393-1-AP from Proteintech Group

Prices $279.00
Sizes con: 51 μg/150μl
Host Rabbit
Clonality Polyclonal
mouse kidney tissue were subjected to SDS PAGE followed by western blot with 10393-1-AP(COMMD5 antibody) at dilution of 1:1000

COMMD5 antibody - STJ26787 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

COMMD5 - MBS9127239 from MyBioSource

Prices $285.00, $555.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal

COMMD5, Polyclonal Antibody - MBS2524358 from MyBioSource

Prices $195.00, $270.00, $435.00
Sizes 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

COMMD5 - A4664 from NeoScientific

Prices $480.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

COMM domain containing 5 , Polyclonal Antibody - MBS712629 from MyBioSource

Prices $230.00, $500.00
Sizes 50 µl, 150 µl
Host Rabbit
Clonality Polyclonal

COMMD5 Antibody - EPP11755 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
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Anti-COMMD5 (aa 125-224) polyclonal antibody - DPAB-DC1462 from Creative Diagnostics

Host Mouse
Clonality Polyclonal

Anti-COMMD5 (N-terminal) polyclonal antibody - DPABH-11964 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal
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