COMMD5

Gene Symbol	COMMD5
Entrez Gene	28991
Alt Symbol	HCARG, HT002
Species	Human
Gene Type	protein-coding
Description	COMM domain containing 5
Other Description	COMM domain-containing protein 5|hypertension-related calcium-regulated gene protein
Swissprots	D3DWN7 Q9GZQ3 Q9UHX5 Q9NVN6
Accessions	CAD34952 CAE90801 EAW82033 EAW82034 EAW82035 EAW82036 EAW82037 Q9GZQ3 AF113540 AAF14877 AF290195 AAG09915 AK001477 BAA91714 AK023070 BAB14389 AK092477 AW137480 BC002672 AAH02672 BC003055 AAH03055 BC065729 AAH65729 BG705627 BI753202 BM013651 BM924244 BQ680339 BU508224 BU600590 H92104 XR_428379 XR_928321 XR_928322 XR_928323 XR_928324 XR_928325 NM_001081003 NP_001074472 NM_001081004 NP_001074473 NM_001287237 NP_001274166 NM_014066 NP_054785
Function	May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity). Down-regulates activation of NF-kappa-B (PubMed:15799966). {ECO:0000250|UniProtKB:Q9ERR2, ECO:0000269|PubMed:15799966, ECO:0000305|PubMed:21778237}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:21778237}. Nucleus {ECO:0000269|PubMed:21778237}.
Tissue Specificity	Highly expressed in heart, stomach, jejunum, kidney, liver, and adrenal gland. Expression was generally higher in adult organs than in fetal tissues, particularly in heart, kidney, and liver. {ECO:0000269|PubMed:10918053, ECO:0000269|PubMed:15799966}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

COMMD5 overexpression lysate - LY415491 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

COMMD5 overexpression lysate - LY421149 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

COMMD5 overexpression lysate - LY421150 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

COMMD5 overexpression lysate - LY425931 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

COMMD5 overexpression lysate - LY429409 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

COMMD5 293 Cell Lysate - 409492 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

COMMD5 Overexpression Lysate (Native) - NBL1-09369 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

COMMD5 Overexpression Lysate (Native) - NBP2-08417 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

COMMD5 Overexpression Lysate (Native) - NBP2-09279 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

COMMD5 Overexpression Lysate (Native) - NBP2-07383 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

COMMD5 Over-expression Lysate Product - GWB-A57B89 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

COMMD5 Overexpression Lysate (Native) - NBP2-09859 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human COMMD5 Knockdown Stable Cell Line - CSC-DC003485 from Creative biogene Category Cell Line Species Human

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