COMMD5

Gene Symbol	COMMD5
Entrez Gene	28991
Alt Symbol	HCARG, HT002
Species	Human
Gene Type	protein-coding
Description	COMM domain containing 5
Other Description	COMM domain-containing protein 5|hypertension-related calcium-regulated gene protein
Swissprots	D3DWN7 Q9GZQ3 Q9UHX5 Q9NVN6
Accessions	CAD34952 CAE90801 EAW82033 EAW82034 EAW82035 EAW82036 EAW82037 Q9GZQ3 AF113540 AAF14877 AF290195 AAG09915 AK001477 BAA91714 AK023070 BAB14389 AK092477 AW137480 BC002672 AAH02672 BC003055 AAH03055 BC065729 AAH65729 BG705627 BI753202 BM013651 BM924244 BQ680339 BU508224 BU600590 H92104 XR_428379 XR_928321 XR_928322 XR_928323 XR_928324 XR_928325 NM_001081003 NP_001074472 NM_001081004 NP_001074473 NM_001287237 NP_001274166 NM_014066 NP_054785
Function	May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity). Down-regulates activation of NF-kappa-B (PubMed:15799966). {ECO:0000250|UniProtKB:Q9ERR2, ECO:0000269|PubMed:15799966, ECO:0000305|PubMed:21778237}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:21778237}. Nucleus {ECO:0000269|PubMed:21778237}.
Tissue Specificity	Highly expressed in heart, stomach, jejunum, kidney, liver, and adrenal gland. Expression was generally higher in adult organs than in fetal tissues, particularly in heart, kidney, and liver. {ECO:0000269|PubMed:10918053, ECO:0000269|PubMed:15799966}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human COMD5 protein fragment - ab162202 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human COMMD5 Protein - H00028991-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

COMMD5 - H00028991-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

COMMD5 - H00028991-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

COMMD5 fusion protein - Ag0592 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

COMMD5 fusion protein - Ag18464 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human COMMD5, GST-tagged - COMMD5-11449H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human COMM domain-containing protein 5(COMMD5) - CSB-YP872415HU CSB-EP872415HU CSB-BP872415HU CSB-MP872415HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

COMMD5 (transcript variant 3) - TP301051 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

COMMD5 (transcript variant 1) - TP309381 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

COMMD5 (transcript variant 2) - TP316768 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

COMMD5 Recombinant Protein Antigen - NBP2-30531PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Source E.coli Species Human

COMMD5 Peptide, Human - M34GP03485H from Creative Peptides Category Peptide Source Synthetic. Species Human

COMMD5 Recombinant Protein Antigen - NBP2-30916PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Source E.coli Species Human

COMM domain-containing protein 5 (COMMD5), Recombinant Protein - MBS1376279 from MyBioSource Category Protein Prices $975.00, $975.00, $1,200.00, $1,200.00, $1,470.00, $1,470.00, $1,935.00, $1,935.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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