Fas

Gene Symbol	Fas
Entrez Gene	246097
Alt Symbol	Tnfrsf6
Species	Rat
Gene Type	protein-coding
Description	Fas cell surface death receptor
Other Description	CD95 antigen|FASLG receptor|Fas (TNF receptor superfamily, member 6)|Fas antigen (ATP1)|Fas receptor|Tumor necrosis factor receptor superfamily, member 6|apo-1 antigen|apoptosis-mediating surface antigen FAS|tumor necrosis factor receptor superfamily member 6
Swissprots	Q63199
Accessions	EDM13158 EDM13159 Q63199 AF104034 AAD20221 CB810875 D26113 BAA05109 FQ233018 NM_139194 NP_631933
Function	Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity). {ECO:0000250}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Top Pathways	Proteoglycans in cancer, Herpes simplex infection, TNF signaling pathway, Influenza A, Non-alcoholic fatty liver disease (NAFLD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat Fas / Tumor Necrosis Factor Receptor Superfamily Member 6 ELISA Kit - RAB0893 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Fas/APO-1, Rat, ELISA Kit - E02F0005 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 250-5000 pg/mL,

Fatty acid synthase (FAS), Rat, ELISA Kit - CSB-E16440r from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Fatty Acid Synthase (FASN), Rat, ELISA Kit - SEC470Ra from ARP American Research Products Category ELISA Kit Prices $780.00 Sizes 96 t Sensitivity 0.127ng/mL Range 0.312-20ng/mL

Tumor necrosis factor receptor superfamily member 6, FAS, Rat, ELISA Kit - E0030r from ARP American Research Products Category ELISA Kit Prices $536.00 Sizes 96 t Range 0.78-50 ng/mL

Custom Rat FAS ELISA - ELR-FAS from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Rat FAS ELISA Kit - RF0053 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Rat FAS ELISA Kit - RF0050 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Rat Fas/APO-1 ELISA Kit - RF0012 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

FAS/CD95, ELISA Kit - MBS2503640 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25--2000pg/mL

Rat FAS/CD95(Factor Related Apoptosis) ELISA Kit - E-EL-R0373 from Elabscience Category ELISA Kit Sensitivity 18.75 pg/mL Range 31.25—2000 pg/mL

Rat FAS/CD95 (Factor Related Apoptosis) CLIA Kit - E-CL-R0243 from Elabscience Category CLIA Kit Sensitivity 7.50 pg/mL Range Average Recovery (%)

Fas (TNF receptor superfamily, member 6) , ELISA Kit - MBS701147 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of rat FAS is typically less than 0.195 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 0.78 ng/ml -50 ng/ml.

Rat Factor-related Apoptosis,FAS ELISA Kit - CSB-E07324r from Cusabio Category ELISA Kit Sensitivity 0.195ng/ml Range 0.78 ng/ml-50 ng/ml

Rat Fas/APO-1 ELISA - E02F0005 from BlueGene Biotech Category ELISA Kit Sensitivity 1.0 pg/mL

Rat Fatty Acid Synthase ELISA - E02F0043 from BlueGene Biotech Category ELISA Kit

ELISA Kit for Fatty Acid Synthase (FASN) - SEC470Ra from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.131ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Rat FAS/CD95(Factor Related Apoptosis) ELISA Kit - E-EL-R0373 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 18.75 pg/mL Range 31.25~2000 pg/mL

Rat FASN(Fatty Acid Synthase) ELISA Kit - E-EL-R0395 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.19 ng/mL Range 0.31~20 ng/mL

Rat COL1*(Collagen Type I)* CLIA Kit - E-CL-R0159 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.938ng/mL Range 1.563-100ng/mL

Rat FAS/CD95 (Factor Related Apoptosis) CLIA Kit - E-CL-R0243 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

Rat PI (Proinsulin) CLIA Kit - E-CL-R0552 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 1.875ng/mL Range 3.125-200ng/mL

Rat FAS ELISA Kit - abx155500 from Abbexa Category ELISA Kit Range 15.63 pg/ml - 1000 pg/ml

Rat Tumor necrosis factor receptor superfamily member 6 ELISA Kit - abx256156 from Abbexa Category ELISA Kit Range 0.78 ng/ml - 50 ng/ml

Factor Related Apoptosis (FAS), Rat, ELISA Kit - DL-FAS-Ra from ARP American Research Products Category ELISA Kit Prices $715.00 Sizes 96 t Range 78-5,000 pg/mL

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