Fas

Gene Symbol Fas
Entrez Gene 246097
Alt Symbol Tnfrsf6
Species Rat
Gene Type protein-coding
Description Fas cell surface death receptor
Other Description CD95 antigen|FASLG receptor|Fas (TNF receptor superfamily, member 6)|Fas antigen (ATP1)|Fas receptor|Tumor necrosis factor receptor superfamily, member 6|apo-1 antigen|apoptosis-mediating surface antigen FAS|tumor necrosis factor receptor superfamily member 6
Swissprots Q63199
Accessions EDM13158 EDM13159 Q63199 AF104034 AAD20221 CB810875 D26113 BAA05109 FQ233018 NM_139194 NP_631933
Function Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Proteoglycans in cancer, Herpes simplex infection, TNF signaling pathway, Influenza A, Non-alcoholic fatty liver disease (NAFLD)

Fas/TNFRSF6/CD95 Antibody [Unconjugated] - AF2159 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal

Fas/TNFRSF6/CD95 Antibody [Biotin] - BAF2159 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

CD95 / FAS antibody - PAB8028 from Acris Antibodies

Prices $420.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FAS - 10-P1119-1 from ARP American Research Products

Host Rabbit
Clonality Polyclonal

CD95, Polyclonal Antibody - MBS175670 from MyBioSource

Prices $245.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

FAS Antibody - 250645 from ABBIOTEC

Prices $277.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

FAS / CD95 / APO-1 / TNFRSF6 Antibody, Rabbit MAb - 80043-R105-50 from Sino Biological

Prices $170.00, $290.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Monoclonal
Clone 105

FAS / CD95 / APO-1 / TNFRSF6 Antibody, Rabbit MAb - 80043-R018-50 from Sino Biological

Prices $170.00, $290.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Monoclonal
Clone 018

CD95 / APO-1 / TNFRSF6 Antibody, Rabbit PAb, Antigen Affinity Purified - 80043-T16-50 from Sino Biological

Prices $170.00, $290.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal
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