HSD11B1

Gene Symbol	HSD11B1
Entrez Gene	3290
Alt Symbol	11-DH, 11-beta-HSD1, CORTRD2, HDL, HSD11, HSD11B, HSD11L, SDR26C1
Species	Human
Gene Type	protein-coding
Description	hydroxysteroid (11-beta) dehydrogenase 1
Other Description	corticosteroid 11-beta-dehydrogenase isozyme 1|short chain dehydrogenase/reductase family 26C member 1|short chain dehydrogenase/reductase family 26C, member 1
Swissprots	P28845 D3DT89 B2R9Z1
Accessions	AAC31757 AAK83653 EAW93445 EAW93446 P28845 AK313973 BAG36688 BC012593 AAH12593 BG619051 BM994393 BX345837 CB530075 CF596989 CF597174 DQ892912 ABM83838 EU176721 ABW03522 KJ534869 AHW56509 NM_001206741 NP_001193670 NM_005525 NP_005516 NM_181755 NP_861420
Function	Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to 7-beta-hydroxycholesterol (By similarity). {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:10497248}; Single-pass type II membrane protein {ECO:0000269|PubMed:10497248}.
Tissue Specificity	Widely expressed. Highest expression in liver.
Top Pathways	Steroid hormone biosynthesis, Chemical carcinogenesis, Metabolism of xenobiotics by cytochrome P450

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

11β-HSD1 (H-100) - sc-20175 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

11β-HSD1 (N-14) - sc-19257 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

11β-HSD1 (C-17) - sc-19259 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-HDL antibody - ab157595 from Abcam Prices $370.00 Sizes 150 µg Host Chicken Clonality Polyclonal

Anti-HDL antibody [1C5] - ab34788 from Abcam Prices $372.00 Sizes 250 µl Host Mouse Clonality Monoclonal Clone 1C5

Anti-HDL antibody (Biotin) - ab51419 from Abcam Prices $370.00 Sizes 150 µg Host Rabbit Clonality Polyclonal

Anti-HDL antibody (Biotin) - ab157416 from Abcam Prices $370.00 Sizes 150 µg Host Chicken Clonality Polyclonal

Anti-HSD11B1 antibody - ab109554 from Abcam Prices $378.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-HSD11B1 antibody - ab27501 from Abcam Prices $379.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-HSD11B1 antibody - ab96724 from Abcam Prices $376.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-HSD11B1 antibody - ab84273 from Abcam Prices $376.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-HSD11B1 antibody - ab55270 from Abcam Host Mouse Clonality Monoclonal

Anti-HSD11B1 antibody - ab39364 from Abcam Prices $392.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-HSD11B1 antibody [EPR9407(2)] - ab157223 from Abcam Prices $384.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR9407(2)

Anti-HDL / High Density Lipoprotein Antibody - LS-C71711 from LifeSpan Bioscience Prices $575.00 Sizes 50 µg Host Mouse Clonality Monoclonal

Anti-HDL / High Density Lipoprotein Antibody - LS-C147201 from LifeSpan Bioscience Prices $270.00 Sizes 1 ml Host Goat Clonality Polyclonal

Anti-HDL / High Density Lipoprotein Antibody (clone M-32) - LS-C193349 from LifeSpan Bioscience Prices $415.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone M-32

Anti-HDL / High Density Lipoprotein Antibody - LS-C195807 from LifeSpan Bioscience Prices $375.00 Sizes 1 ml Host Goat Clonality Polyclonal

Anti-HDL / High Density Lipoprotein Antibody (FITC) - LS-C304596 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-HDL / High Density Lipoprotein Antibody - LS-C294501 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-HDL / High Density Lipoprotein Antibody (Biotin) - LS-C305789 from LifeSpan Bioscience Prices $415.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-HSD11B1 / HSD11B Antibody (aa16-33) - LS-C343882 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-HSD11B1 / HSD11B Antibody - LS-C335178 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-HSD11B1 / HSD11B Antibody (clone 2C10) - LS-C197461 from LifeSpan Bioscience Prices $355.00 Sizes 200 µl Host Mouse Clonality Monoclonal Clone 2C10

Anti-HSD11B1 / HSD11B Antibody (aa64-77) - LS-C154869 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Goat Clonality Polyclonal

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