HSD11B1

Gene Symbol	HSD11B1
Entrez Gene	3290
Alt Symbol	11-DH, 11-beta-HSD1, CORTRD2, HDL, HSD11, HSD11B, HSD11L, SDR26C1
Species	Human
Gene Type	protein-coding
Description	hydroxysteroid (11-beta) dehydrogenase 1
Other Description	corticosteroid 11-beta-dehydrogenase isozyme 1|short chain dehydrogenase/reductase family 26C member 1|short chain dehydrogenase/reductase family 26C, member 1
Swissprots	P28845 D3DT89 B2R9Z1
Accessions	AAC31757 AAK83653 EAW93445 EAW93446 P28845 AK313973 BAG36688 BC012593 AAH12593 BG619051 BM994393 BX345837 CB530075 CF596989 CF597174 DQ892912 ABM83838 EU176721 ABW03522 KJ534869 AHW56509 NM_001206741 NP_001193670 NM_005525 NP_005516 NM_181755 NP_861420
Function	Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to 7-beta-hydroxycholesterol (By similarity). {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:10497248}; Single-pass type II membrane protein {ECO:0000269|PubMed:10497248}.
Tissue Specificity	Widely expressed. Highest expression in liver.
Top Pathways	Steroid hormone biosynthesis, Chemical carcinogenesis, Metabolism of xenobiotics by cytochrome P450

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HDL / High Density Lipoprotein ELISA Kit (Sandwich ELISA) - LS-F4387 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.9 ng/ml Range 2.34-150 ng/ml

Rat HDL / High Density Lipoprotein ELISA Kit (Sandwich ELISA) - LS-F4906 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 1.39 ng/ml Range 2.34-150 ng/ml

Mouse HDL / High Density Lipoprotein ELISA Kit (Sandwich ELISA) - LS-F5778 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.38 ng/ml Range 2.34-150 ng/ml

Human HDL / High Density Lipoprotein ELISA Kit (Sandwich ELISA) - LS-F10581 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 125 Range 2.34-150 ng/ml

Human HSD11B1 / HSD11B ELISA Kit (Sandwich ELISA) - LS-F6985 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.59 ng/ml Range 1.56-100 ng/ml

Rat HSD11B1 / HSD11B ELISA Kit (Sandwich ELISA) - LS-F7409 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.124 ng/ml Range 1.56-100 ng/ml

Human HSD11B1 / HSD11B ELISA Kit (Sandwich ELISA) - LS-F11298 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 1.56-100 ng/ml

HDL/LDL Quantification Kit - 55R-1456 from Fitzgerald Prices $509.00 Sizes 100 assays

Human HDL ELISA Kit - abx151781 from Abbexa Category ELISA Kit Sensitivity 42.35 ng/ml Range 93.75 ng/ml - 6000 ng/ml

Human HSD11b1 ELISA Kit - abx151849 from Abbexa Category ELISA Kit Sensitivity 0.57 ng/ml Range 1.563 ng/ml - 100 ng/ml

11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1), Human, ELISA Kit - SEC268Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.047ng/mL Range 0.156-10ng/mL

11-Beta-Hydroxysteroid Dehydrogenase Type 2 (HSD11b2), Human, ELISA Kit - SEF183Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.057ng/mL Range 0.156-10ng/mL

11-Beta-Hydroxysteroid Dehydrogenase Type 3 (HSD11b3), Human, ELISA Kit - SEV001Hu from ARP American Research Products Category ELISA Kit Prices $790.00 Sizes 96 t Sensitivity 0.065ng/mL Range 0.156-10ng/mL

Corticosteroid 11-beta-dehydrogenase isozyme 1 (HSD11B1), Human, ELISA Kit - CSB-E13741h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Corticosteroid 11-beta-dehydrogenase isozyme 1, HSD11B1, Human, ELISA Kit - E2268h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

High density lipoprotein (HDL), Human, ELISA Kit - CSB-E16550h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

High Density Lipoprotein (HDL), Human, ELISA Kit - SEB006Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity in contrast to "bad"" LDL cholesterol. Range any contained in HDL particles is considered as protection to the bodys cardiovascular health

High-density lipoprotein, HDL, Human, ELISA Kit - E1006h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 1.56-100 ng/mL

High Density Lipoprotein, HDL, Mouse, ELISA Kit - E-EL-M1402 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 1.875 Range 3.125-200nmol/mL

High Density Lipoprotein (HDL), Mouse, ELISA Kit - SEB006Mu from ARP American Research Products Category ELISA Kit Prices $704.00 Sizes 96 t Sensitivity in contrast to "bad"" LDL cholesterol. Range any contained in HDL particles is considered as protection to the bodys cardiovascular health

High Density Lipoprotein, HDL, Rat, ELISA Kit - E-EL-R0504 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 1.875 Range 3.125-200ng/mL

High Density Lipoprotein (HDL), Rat, ELISA Kit - SEB006Ra from ARP American Research Products Category ELISA Kit Prices $742.00 Sizes 96 t Sensitivity in contrast to "bad"" LDL cholesterol. Range any contained in HDL particles is considered as protection to the bodys cardiovascular health

HDL (Human) ELISA Kit - KA2117 from Acris Antibodies Category ELISA Kit Prices $650.00 Sizes 1 kit

Human HDL ELISA Kit - HH0218 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine HDL ELISA Kit - AH0218 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

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