HSD11B1

Gene Symbol	HSD11B1
Entrez Gene	3290
Alt Symbol	11-DH, 11-beta-HSD1, CORTRD2, HDL, HSD11, HSD11B, HSD11L, SDR26C1
Species	Human
Gene Type	protein-coding
Description	hydroxysteroid (11-beta) dehydrogenase 1
Other Description	corticosteroid 11-beta-dehydrogenase isozyme 1|short chain dehydrogenase/reductase family 26C member 1|short chain dehydrogenase/reductase family 26C, member 1
Swissprots	P28845 D3DT89 B2R9Z1
Accessions	AAC31757 AAK83653 EAW93445 EAW93446 P28845 AK313973 BAG36688 BC012593 AAH12593 BG619051 BM994393 BX345837 CB530075 CF596989 CF597174 DQ892912 ABM83838 EU176721 ABW03522 KJ534869 AHW56509 NM_001206741 NP_001193670 NM_005525 NP_005516 NM_181755 NP_861420
Function	Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7- ketocholesterol to 7-beta-hydroxycholesterol (By similarity). {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:10497248}; Single-pass type II membrane protein {ECO:0000269|PubMed:10497248}.
Tissue Specificity	Widely expressed. Highest expression in liver.
Top Pathways	Steroid hormone biosynthesis, Chemical carcinogenesis, Metabolism of xenobiotics by cytochrome P450

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HSD11B1 - MBS1275955 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC012593

Human HSD11B1 ORF Clone(NM_005525.3) - CDCL166512 from Creative Biomart Species Human Accession NM_005525.3

Human HSD11B1 Gene ORF cDNA clone in cloning vector - HG14796-G from Sino Biological Species Human

Human HSD11B1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14796-ACG from Sino Biological Species Human

Human HSD11B1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14796-NY from Sino Biological Species Human

Human HSD11B1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14796-ACR from Sino Biological Species Human

Human HSD11B1 Gene ORF cDNA clone expression plasmid, N-His tag - HG14796-NH from Sino Biological Species Human

Human HSD11B1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14796-NF from Sino Biological Species Human

Human HSD11B1 Gene ORF cDNA clone expression plasmid, C-His tag - HG14796-CH from Sino Biological Species Human

Human HSD11B1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14796-CF from Sino Biological Species Human

Human HSD11B1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14796-NM from Sino Biological Species Human

Human HSD11B1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14796-CM from Sino Biological Species Human

Human HSD11B1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14796-CY from Sino Biological Species Human

Human HSD11B1 natural ORF mammalian expression plasmid - HG14796-UT from Sino Biological Species Human Accession BC012593

Human HSD11B1 ORF Clone (BC012593) - CDCS409667 from Creative biogene Species Human Accession P28845

Human HSD11B1 ORF clone (BC012593) - CDCB158775 from Creative biogene Species Human

Human HSD11B1 Gene cDNA Clone - orb143620 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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