NEK3

Gene Symbol NEK3
Entrez Gene 4752
Alt Symbol HSPK36
Species Human
Gene Type protein-coding
Description NIMA-related kinase 3
Other Description HSPK 36|NIMA (never in mitosis gene a)-related kinase 3|glycogen synthase A kinase|hydroxyalkyl-protein kinase|never in mitosis A-related kinase 3|nimA-related protein kinase 3|phosphorylase B kinase kinase|serine/threonine-protein kinase Nek3
Swissprots Q8WUN5 Q8J023 P51956 A8K2J4 Q5TAP2
Accessions EAX08905 EAX08906 EAX08907 EAX08908 EAX08909 P51956 AB072828 BAC15599 AI026881 AI209040 AK131359 BAD18511 AK290259 BAF82948 AL833951 CAI46210 AW364762 BC019916 AAH19916 BM675414 BM984985 BQ648157 BX395059 CV029372 DA407862 DA733733 DB185803 DQ891803 ABM82729 DQ894987 ABM85913 H15146 Z25434 CAA80921 Z29067 CAA82310 NM_001146099 NP_001139571 NM_002498 NP_002489 NM_152720 NP_689933 NR_027415
Function Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin- mediated phosphorylation of PXN and VAV2. Implicated in prolactin- mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2. {ECO:0000269|PubMed:15618286, ECO:0000269|PubMed:17297458}.
Subcellular Location Cytoplasm {ECO:0000250}. Cell projection, axon {ECO:0000250}.
Tissue Specificity Up-regulated in malignant versus normal breast tissue. Isoform 2 shows a high level of expression in testis, ovary and brain. {ECO:0000269|PubMed:12063396, ECO:0000269|PubMed:17297458}.

Nek3 (C-20) - sc-7441 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Nek3 (C-20): sc-7441. Western blot analysis of Nek3 expression in COLO 320DM whole cell lysate.

Nek3 (E-10) - sc-390872 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nek3 (E-10): sc-390872. Western blot analysis of Nek3 expression in COLO 320DM (A) and MCF7 (B) whole cell lysates.

Nek3 (H-49) - sc-292542 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Nek3 (9-7K) - sc-100402 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Nek3 (9-7K): sc-100402. Western blot analysis of Nek3 expression in non-transfected: sc-117752 (A) and human Nek3 transfected: sc-113934 (B) 293T whole cell lysates.

Anti-NEK3 antibody - ab37636 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-NEK3 antibody (ab37636) + CEM cell lysate at 35 µg

Anti-NEK3 antibody - ab55567 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab55567 NEK3 antibody at 1ug/ml.

Anti-NEK3 Antibody (aa446-474, AP) - LS-C264184 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK3 Antibody (aa446-474, APC) - LS-C264185 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK3 Antibody (aa446-474, Biotin) - LS-C264186 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK3 Antibody (aa446-474, FITC) - LS-C264187 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK3 Antibody (aa446-474, Azide-free, HRP) - LS-C264188 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK3 Antibody (aa108-157) - LS-C102330 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NEK3 antibody LS-C102330 Western blot of HeLa lysate.

Anti-NEK3 Antibody (aa446-474, PE) - LS-C264189 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK3 Antibody (aa339-368, APC) - LS-C264190 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK3 Antibody (aa339-368, AP) - LS-C264191 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK3 Antibody (aa339-368, Biotin) - LS-C264192 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK3 Antibody (aa339-368, FITC) - LS-C264193 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK3 Antibody (aa339-368, PE) - LS-C264194 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK3 Antibody (aa339-368, Azide-free, HRP) - LS-C264197 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK3 Antibody (aa445-474) - LS-C323285 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK3 Antibody (aa339-368) - LS-C323288 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK3 Antibody - LS-C334861 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using NEK3 antibody.

Anti-NEK3 Antibody (aa446-474) - LS-C164495 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Mouse Nek3 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded mouse brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-NEK3 Antibody (clone 2F8) - LS-C197766 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2F8
Immunofluorescence of monoclonal antibody to NEK3 on HeLa cell. [antibody concentration 10 ug/ml]

NEK3 Antibody (2F8) - H00004752-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2F8
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