NEK3

Gene Symbol	NEK3
Entrez Gene	4752
Alt Symbol	HSPK36
Species	Human
Gene Type	protein-coding
Description	NIMA-related kinase 3
Other Description	HSPK 36|NIMA (never in mitosis gene a)-related kinase 3|glycogen synthase A kinase|hydroxyalkyl-protein kinase|never in mitosis A-related kinase 3|nimA-related protein kinase 3|phosphorylase B kinase kinase|serine/threonine-protein kinase Nek3
Swissprots	Q8WUN5 Q8J023 P51956 A8K2J4 Q5TAP2
Accessions	EAX08905 EAX08906 EAX08907 EAX08908 EAX08909 P51956 AB072828 BAC15599 AI026881 AI209040 AK131359 BAD18511 AK290259 BAF82948 AL833951 CAI46210 AW364762 BC019916 AAH19916 BM675414 BM984985 BQ648157 BX395059 CV029372 DA407862 DA733733 DB185803 DQ891803 ABM82729 DQ894987 ABM85913 H15146 Z25434 CAA80921 Z29067 CAA82310 NM_001146099 NP_001139571 NM_002498 NP_002489 NM_152720 NP_689933 NR_027415
Function	Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin- mediated phosphorylation of PXN and VAV2. Implicated in prolactin- mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2. {ECO:0000269|PubMed:15618286, ECO:0000269|PubMed:17297458}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cell projection, axon {ECO:0000250}.
Tissue Specificity	Up-regulated in malignant versus normal breast tissue. Isoform 2 shows a high level of expression in testis, ovary and brain. {ECO:0000269|PubMed:12063396, ECO:0000269|PubMed:17297458}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HSPK 36 Gene - orb91519 from Biorbyt Prices $519.00 Sizes 10 μg Species Human

Human-NEK3-cDNA-Clone - DC04859 from Abgent, a WuXi AppTec company Prices $661.50 Sizes 10 µg Species Human Accession NM_001146099

NEK3 cDNA (ANA11267) - ANA11267 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC019916

NEK3 - MBS1271186 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC019916

Human NEK3 cDNA clone(NM_001146099.1) - CDFH012401 from Creative Biomart Species Human Accession NM_001146099.1

Human NEK3 ORF Clone(NM_001146099.1) - CDCR353257 from Creative Biomart Species Human Accession NM_001146099.1

Human NEK3 ORF Clone(NM_001146099.1) - CDCR353258 from Creative Biomart Species Human Accession NM_001146099.1

Human NEK3 transcript variant 2 Gene ORF cDNA clone in cloning vector - HG10675-M from Sino Biological Species Human

Human NEK3 transcript variant 2 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG10675-M-N from Sino Biological Species Human Accession NM_152720.1

Human NEK3 transcript variant 2 Gene ORF cDNA clone expression plasmid - HG10675-UT from Sino Biological Species Human

Human NEK3 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10675-ANG from Sino Biological Species Human

Human NEK3 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10675-M-F from Sino Biological Species Human

Human NEK3 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-His tag - HG10675-NH from Sino Biological Species Human

Human NEK3 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10675-NF from Sino Biological Species Human

Human NEK3 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10675-NM from Sino Biological Species Human

Human NEK3 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10675-CY from Sino Biological Species Human

Human NEK3 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10675-ACG from Sino Biological Species Human

Human NEK3 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10675-CF from Sino Biological Species Human

Human NEK3 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10675-CM from Sino Biological Species Human

Human NEK3 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10675-NY from Sino Biological Species Human

Human NEK3 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-His tag - HG10675-CH from Sino Biological Species Human

Human NEK3 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10675-ACR from Sino Biological Species Human

Human NEK3 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10675-ANR from Sino Biological Species Human

Human NEK3 ORF clone (NM_001146099.1) - CDCL137583 from Creative biogene Species Human

Human NEK3 ORF Clone (BC019916) - CDCS408587 from Creative biogene Species Human Accession P51956

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