NEK3

Gene Symbol	NEK3
Entrez Gene	4752
Alt Symbol	HSPK36
Species	Human
Gene Type	protein-coding
Description	NIMA-related kinase 3
Other Description	HSPK 36|NIMA (never in mitosis gene a)-related kinase 3|glycogen synthase A kinase|hydroxyalkyl-protein kinase|never in mitosis A-related kinase 3|nimA-related protein kinase 3|phosphorylase B kinase kinase|serine/threonine-protein kinase Nek3
Swissprots	Q8WUN5 Q8J023 P51956 A8K2J4 Q5TAP2
Accessions	EAX08905 EAX08906 EAX08907 EAX08908 EAX08909 P51956 AB072828 BAC15599 AI026881 AI209040 AK131359 BAD18511 AK290259 BAF82948 AL833951 CAI46210 AW364762 BC019916 AAH19916 BM675414 BM984985 BQ648157 BX395059 CV029372 DA407862 DA733733 DB185803 DQ891803 ABM82729 DQ894987 ABM85913 H15146 Z25434 CAA80921 Z29067 CAA82310 NM_001146099 NP_001139571 NM_002498 NP_002489 NM_152720 NP_689933 NR_027415
Function	Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin- mediated phosphorylation of PXN and VAV2. Implicated in prolactin- mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2. {ECO:0000269|PubMed:15618286, ECO:0000269|PubMed:17297458}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cell projection, axon {ECO:0000250}.
Tissue Specificity	Up-regulated in malignant versus normal breast tissue. Isoform 2 shows a high level of expression in testis, ovary and brain. {ECO:0000269|PubMed:12063396, ECO:0000269|PubMed:17297458}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human NEK3 full length protein - ab89758 from Abcam Category Protein Prices $302.00, $352.00 Sizes 5 µg, 10 µg Source Baculovirus infected sf9 cells Species Human

Human NEK3 full length protein - ab158987 from Abcam Category Protein Source Wheat germ Species Human

Human NEK3 protein fragment - ab158988 from Abcam Category Protein Source Wheat germ Species Human

NEK3 Antibody Blocking Peptide - LS-E2815 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NEK3 Antibody Blocking Peptide - LS-E17751 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NEK3 Partial Recombinant Protein - H00004752-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

NEK3 Recombinant Protein - H00004752-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

NEK3 Blocking Peptide - 33R-3099 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NEK3 - H00004752-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NEK3 - H00004752-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NEK3 - H00004752-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NEK3 - H00004752-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NEK3 - P5611 from Acris Antibodies Category Protein Prices $840.00 Sizes 5 µg Species Human

NEK3 fusion protein - ag3856 from Proteintech Group Category Protein Source E. coli-derived, T-HIS Species Human

Recombinant Human NEK3 - NEK3-29620TH from Creative Biomart Category Protein

Recombinant Human NEK3, GST-tagged, Active - NEK3-369H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus.

NEK3 Protein, active, 10 µg - 14-694 from EMD Millipore Category Protein Prices $311.00 Sizes 10 µg Source Human NEK3, expressed by baculovirus in Sf21 cells.

Recombinant Human Serine/threonine-protein kinase Nek3(NEK3) - CSB-YP015701HU CSB-EP015701HU CSB-BP015701HU CSB-MP015701HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human NEK3 His - CSI13441 from Cell Science Prices $615.00 Sizes 10 μg Species Human

NEK3 Protein - NBP2-13650PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

NEK3 Recombinant Protein Antigen - NBP2-13649PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NEK3 Protein, active, 250 µg - 14-694M from EMD Millipore Category Protein Prices $2,544.00 Sizes 250 µg also available in 10 μg size . (cat#14-694) and in bulk (cat# 14-694-K) Source Human NEK3, expressed by baculovirus in Sf21 cells.

NEK3-Antibody-Center-Blocking-Peptide - BP8075c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NEK3 Peptide, Human - M34GP10290H from Creative Peptides Category Peptide Source Synthetic. Species Human

NEK3, Recombinant Protein - MBS2546599 from MyBioSource Category Protein Prices $525.00, $675.00 Sizes 20 µg, 50 µg Source Baculovirus-Insect Cells

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