NEK3

Gene Symbol NEK3
Entrez Gene 4752
Alt Symbol HSPK36
Species Human
Gene Type protein-coding
Description NIMA-related kinase 3
Other Description HSPK 36|NIMA (never in mitosis gene a)-related kinase 3|glycogen synthase A kinase|hydroxyalkyl-protein kinase|never in mitosis A-related kinase 3|nimA-related protein kinase 3|phosphorylase B kinase kinase|serine/threonine-protein kinase Nek3
Swissprots Q8WUN5 Q8J023 P51956 A8K2J4 Q5TAP2
Accessions EAX08905 EAX08906 EAX08907 EAX08908 EAX08909 P51956 AB072828 BAC15599 AI026881 AI209040 AK131359 BAD18511 AK290259 BAF82948 AL833951 CAI46210 AW364762 BC019916 AAH19916 BM675414 BM984985 BQ648157 BX395059 CV029372 DA407862 DA733733 DB185803 DQ891803 ABM82729 DQ894987 ABM85913 H15146 Z25434 CAA80921 Z29067 CAA82310 NM_001146099 NP_001139571 NM_002498 NP_002489 NM_152720 NP_689933 NR_027415
Function Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin- mediated phosphorylation of PXN and VAV2. Implicated in prolactin- mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2. {ECO:0000269|PubMed:15618286, ECO:0000269|PubMed:17297458}.
Subcellular Location Cytoplasm {ECO:0000250}. Cell projection, axon {ECO:0000250}.
Tissue Specificity Up-regulated in malignant versus normal breast tissue. Isoform 2 shows a high level of expression in testis, ovary and brain. {ECO:0000269|PubMed:12063396, ECO:0000269|PubMed:17297458}.

NEK3-Over-expression-Lysate - LY10654a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag NEK3 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NEK3 gene (Lane 2, Cat. #LY10654a).

NEK3 293T Cell Transient Overexpression Lysate(Denatured) - H00004752-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

NEK3 overexpression lysate - LY419289 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

NEK3 overexpression lysate - LY429108 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

NEK3 overexpression lysate - LY431430 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

NEK3 293 Cell Lysate - 404206 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

NEK3 Overexpression Lysate (Native) - NBL1-13584 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: NEK3 Overexpression Lysate (Adult Normal) [NBL1-13584] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NEK3.

NEK3 Overexpression Lysate (Native) - NBP2-08110 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: NEK3 Overexpression Lysate (Adult Normal) [NBP2-08110] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NEK3.

Nek3 (h): 293T Lysate - sc-113934 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

NEK3 Over-expression Lysate Product - GWB-943AA6 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

NEK3 Overexpression Lysate (Native) - NBP2-09784 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: NEK3 Overexpression Lysate (Adult Normal) [NBP2-09784] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NEK3.

NEK3 Overexpression Lysate (Denatured) - H00004752-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human NEK3 Knockdown Stable Cell Line - CSC-DC010290 from Creative biogene

Category Cell Line
Species Human
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