NEK3

Gene Symbol NEK3
Entrez Gene 4752
Alt Symbol HSPK36
Species Human
Gene Type protein-coding
Description NIMA-related kinase 3
Other Description HSPK 36|NIMA (never in mitosis gene a)-related kinase 3|glycogen synthase A kinase|hydroxyalkyl-protein kinase|never in mitosis A-related kinase 3|nimA-related protein kinase 3|phosphorylase B kinase kinase|serine/threonine-protein kinase Nek3
Swissprots Q8WUN5 Q8J023 P51956 A8K2J4 Q5TAP2
Accessions EAX08905 EAX08906 EAX08907 EAX08908 EAX08909 P51956 AB072828 BAC15599 AI026881 AI209040 AK131359 BAD18511 AK290259 BAF82948 AL833951 CAI46210 AW364762 BC019916 AAH19916 BM675414 BM984985 BQ648157 BX395059 CV029372 DA407862 DA733733 DB185803 DQ891803 ABM82729 DQ894987 ABM85913 H15146 Z25434 CAA80921 Z29067 CAA82310 NM_001146099 NP_001139571 NM_002498 NP_002489 NM_152720 NP_689933 NR_027415
Function Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin- mediated phosphorylation of PXN and VAV2. Implicated in prolactin- mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2. {ECO:0000269|PubMed:15618286, ECO:0000269|PubMed:17297458}.
Subcellular Location Cytoplasm {ECO:0000250}. Cell projection, axon {ECO:0000250}.
Tissue Specificity Up-regulated in malignant versus normal breast tissue. Isoform 2 shows a high level of expression in testis, ovary and brain. {ECO:0000269|PubMed:12063396, ECO:0000269|PubMed:17297458}.

Nek3 CRISPR/Cas9 KO Plasmid (h) - sc-410545 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek3 HDR Plasmid (h) - sc-410545-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek3 Double Nickase Plasmid (h) - sc-410545-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek3 Double Nickase Plasmid (h2) - sc-410545-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek3 CRISPR Activation Plasmid (h) - sc-410545-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek3 CRISPR Activation Plasmid (h2) - sc-410545-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek3 Lentiviral Activation Particles (h) - sc-410545-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek3 Lentiviral Activation Particles (h2) - sc-410545-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nek3 siRNA (h) - sc-43550 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NEK3 shRNA Plasmid (h) - sc-43550-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NEK3 shRNA (h) Lentiviral Particles - sc-43550-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NEK3 RNAi - H00004752-R06 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

NEK3 RNAi - H00004752-R05 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU094251 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK1398 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1397 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1396 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN15200 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15200 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR13007 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr13007

NEK3 siRNA (Human) - CRH3155 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NEK3 (NM_152720.2) - SHH351240 from Creative biogene

Category siRNA
Species Reactivities Human

Human NEK3 siRNA - orb263657 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NEK3 shRNA Plasmid (Human) - CHH3155 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NEK3 miRNA 3'UTR clone - MiUTR1H-06719 from Creative biogene

Species Reactivities Human
Search more