LYVE1

Gene Symbol	LYVE1
Entrez Gene	10894
Alt Symbol	CRSBP-1, HAR, LYVE-1, XLKD1
Species	Human
Gene Type	protein-coding
Description	lymphatic vessel endothelial hyaluronan receptor 1
Other Description	cell surface retention sequence binding protein-1|cell surface retention sequence-binding protein 1|extracellular link domain containing 1|extracellular link domain-containing 1|extracellular link domain-containing protein 1|hyaluronic acid receptor|lymphatic vessel endothelial hyaluronic acid receptor 1
Swissprots	Q9Y5Y7 Q8TC18 Q9UNF4
Accessions	CAI72127 EAW68565 Q9Y5Y7 AF118108 AAD42764 AF127670 AAD49220 AK075443 BAG52138 AK300885 BAG62527 AK312462 BAG35369 AY358925 AAQ89284 BC026231 AAH26231 CA449932 DA924658 DQ892040 ABM82966 DQ895232 ABM86158 NM_006691 NP_006682
Function	Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. {ECO:0000269|PubMed:10037799}.
Subcellular Location	Membrane {ECO:0000269|PubMed:10037799}; Single-pass type I membrane protein {ECO:0000269|PubMed:10037799}. Note=Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand- dependent internalization and recycling at the cell surface.
Tissue Specificity	Mainly expressed in endothelial cells lining lymphatic vessels. {ECO:0000269|PubMed:10037799}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LYVE1 protein fragment - ab75537 from Abcam Category Protein Source E. coli Species Human

Human LYVE1 protein fragment - ab54341 from Abcam Category Protein Source Insect cells Species Human

Human LYVE1 protein fragment - ab87356 from Abcam Category Protein Source Baculovirus infected High-5 cells Species Human

Mouse LYVE1 peptide - ab34093 from Abcam Category Peptide

Mouse LYVE1 protein fragment - ab54342 from Abcam Category Protein Source Insect cells Species Mouse

LYVE1 Antibody Blocking Peptide - LS-E17007 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LYVE1 Antibody Blocking Peptide - LS-E6805 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LYVE1 Antibody Blocking Peptide - LS-E6806 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LYVE-1 Blocking Peptide - NB100-725PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg

LYVE-1 Blocking Peptide - NB100-726PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

LYVE-1 Recombinant Protein - H00010894-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human LYVE-1 Protein - NBC1-18514 from Novus Biologicals Category Protein Prices $529.00 Sizes 50 µg Species Human

LYVE-1 Peptide - P0806 from Novus Biologicals Category Peptide Species Human

LYVE-1 Peptide - P0805 from Novus Biologicals Category Peptide Species Human

LYVE1-XLKD1-Antibody-C-term-Blocking-peptide - BP2015b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

XLKD1-Antibody-N-term-Blocking-Peptide - BP2015a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human LYVE-1, CF - 2089-LY-025 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ser24-Thr238, with a C-terminal 6-His tag

LYVE1 Protein (OPPA01163) - OPPA01163 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source Insect Cells

LYVE1 Protein (OPPA01165) - OPPA01165 from Aviva Systems Biology Category Protein Prices $315.00 Sizes 2 µg Source E. Coli

LYVE1 Human 25-235 a.a. Protein (OPPA01709) - OPPA01709 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source Hi-5 Insect Cells Species Human

Human LYVE1 protein - orb49523 from Biorbyt Category Protein Prices $349.00, $536.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source HEK293

Human LYVE1 protein - orb80829 from Biorbyt Category Protein Prices $366.00, $400.00, $612.00 Sizes 5 μg, 2 μg, 10 μg Species Human

LYVE1 Blocking Peptide - 33R-1461 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

LYVE1 protein - 30R-AL010 from Fitzgerald Category Protein Prices $175.00 Sizes 20 µg Source Sf-9 insect cells

LYVE1 protein (His tag) - 80R-1071 from Fitzgerald Category Protein Prices $515.00 Sizes 50 µg Source Hi-5 cells

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