LYVE1

Gene Symbol LYVE1
Entrez Gene 10894
Alt Symbol CRSBP-1, HAR, LYVE-1, XLKD1
Species Human
Gene Type protein-coding
Description lymphatic vessel endothelial hyaluronan receptor 1
Other Description cell surface retention sequence binding protein-1|cell surface retention sequence-binding protein 1|extracellular link domain containing 1|extracellular link domain-containing 1|extracellular link domain-containing protein 1|hyaluronic acid receptor|lymphatic vessel endothelial hyaluronic acid receptor 1
Swissprots Q9Y5Y7 Q8TC18 Q9UNF4
Accessions CAI72127 EAW68565 Q9Y5Y7 AF118108 AAD42764 AF127670 AAD49220 AK075443 BAG52138 AK300885 BAG62527 AK312462 BAG35369 AY358925 AAQ89284 BC026231 AAH26231 CA449932 DA924658 DQ892040 ABM82966 DQ895232 ABM86158 NM_006691 NP_006682
Function Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. {ECO:0000269|PubMed:10037799}.
Subcellular Location Membrane {ECO:0000269|PubMed:10037799}; Single-pass type I membrane protein {ECO:0000269|PubMed:10037799}. Note=Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand- dependent internalization and recycling at the cell surface.
Tissue Specificity Mainly expressed in endothelial cells lining lymphatic vessels. {ECO:0000269|PubMed:10037799}.

LYVE-1 (E-20) - sc-19316 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LYVE-1 (E-20): sc-19316. Immunoperoxidase staining of formalin fixed, paraffin-embedded human colon tissue showing membrane and cytoplasmic staining of glandular cells and endothelial cells.

LYVE-1 (H-156) - sc-28190 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LYVE-1 (H-156): sc-28190. Western blot analysis of LYVE-1 expression in Hs 294T (A) and SK-N-MC (B) whole cell lysates.

LYVE-1 (M-14) - sc-31293 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LYVE-1 (M-14): sc-31293. Western blot analysis of LYVE-1 expression in MCF7 whole cell lysate.

LYVE-1 (E-13) - sc-31289 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LYVE-1 (P-14) - sc-31290 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LYVE-1 (P-14): sc-31290. Western blot analysis of LYVE-1 expression in MCF7 whole cell lysate (A) and mouse lymph node tissue extract (B).

LYVE-1 (V-15) - sc-31292 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-LYVE1 antibody - ab14917 from Abcam

Prices $401.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab14917 staining LYVE1 in Rabbit spleen tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with paraformaldehyde and blocked with 5% BSA for 30 minutes at 20°C; antigen retrieval was by heat mediation in a citrate buffer. Samples were incubated with primary antibody (1/200 in Fa.Zytomed) for 24 hours at 4°C. An undiluted Biotin-conjugated anti-rabbit IgG polyclonal was used as the secondary antibody.See Abreview

Anti-LYVE1 antibody - ab36993 from Abcam

Prices $390.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
IHC with paraffin-embedded sections of human intestine (border area of a colon carcinoma) using antibody ab36993.

Anti-LYVE1 antibody - ab104620 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-LYVE1 antibody (ab104620) at 1/500 dilutionLane 1 : MCF cell extract with Immunogenic PeptideLane 2 : MCF cell extractObserved band size : 40 kDa (why is the actual band size different from the predicted?)

Anti-LYVE1 antibody [4G1] - ab33477 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4G1
Anti-LYVE1 antibody [4G1] (ab33477) at 1/500 dilution + A549 (lung carcinoma) cell lysateSecondarygoat anti-mouse secondary antibody conjugated to HRPdeveloped using the ECL technique

Anti-LYVE1 antibody [EPR13067(2)] - ab183501 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13067(2)
All lanes : Anti-LYVE1 antibody [EPR13067(2)] (ab183501) at 1/5000 dilutionLane 1 : Human tonsil lysateLane 2 : A549 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-LYVE1 antibody - Lymphatic Vessel Marker - ab10278 from Abcam

Prices $382.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Frozen sections) analysis of human colon carcinoma tissue sections labelling LYVE1 with ab10278.

Anti-LYVE1 Antibody (HRP) - LS-C181013 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LYVE1 Antibody (clone 4D17) - LS-C195201 from LifeSpan Bioscience

Prices $620.00
Sizes 100 µg
Host Rabbit
Clonality Monoclonal
Clone 4D17

Anti-LYVE1 Antibody (N-Terminus, AP) - LS-C244953 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LYVE1 Antibody (N-Terminus, APC) - LS-C244954 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LYVE1 Antibody (aa250-318) - LS-C2571 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of LYVE-1 in endothelial cells of human lung blood vessels. ECL detection overnight.

Anti-LYVE1 Antibody (N-Terminus, PE) - LS-C244956 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LYVE1 Antibody (N-Terminus, FITC) - LS-C244955 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LYVE1 Antibody (aa250-279, AP) - LS-C244957 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LYVE1 Antibody (aa250-279, FITC) - LS-C244960 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LYVE1 Antibody (aa250-279, APC) - LS-C244958 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LYVE1 Antibody (aa250-279, PE) - LS-C244962 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LYVE1 Antibody (N-Terminus) - LS-C327787 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LYVE1 Antibody (C-Terminus) - LS-C327788 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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