LYVE1

Gene Symbol LYVE1
Entrez Gene 10894
Alt Symbol CRSBP-1, HAR, LYVE-1, XLKD1
Species Human
Gene Type protein-coding
Description lymphatic vessel endothelial hyaluronan receptor 1
Other Description cell surface retention sequence binding protein-1|cell surface retention sequence-binding protein 1|extracellular link domain containing 1|extracellular link domain-containing 1|extracellular link domain-containing protein 1|hyaluronic acid receptor|lymphatic vessel endothelial hyaluronic acid receptor 1
Swissprots Q9Y5Y7 Q8TC18 Q9UNF4
Accessions CAI72127 EAW68565 Q9Y5Y7 AF118108 AAD42764 AF127670 AAD49220 AK075443 BAG52138 AK300885 BAG62527 AK312462 BAG35369 AY358925 AAQ89284 BC026231 AAH26231 CA449932 DA924658 DQ892040 ABM82966 DQ895232 ABM86158 NM_006691 NP_006682
Function Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. {ECO:0000269|PubMed:10037799}.
Subcellular Location Membrane {ECO:0000269|PubMed:10037799}; Single-pass type I membrane protein {ECO:0000269|PubMed:10037799}. Note=Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand- dependent internalization and recycling at the cell surface.
Tissue Specificity Mainly expressed in endothelial cells lining lymphatic vessels. {ECO:0000269|PubMed:10037799}.

LYVE-1 CRISPR/Cas9 KO Plasmid (h) - sc-401446 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYVE-1 HDR Plasmid (h) - sc-401446-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYVE-1 Double Nickase Plasmid (h) - sc-401446-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYVE-1 Double Nickase Plasmid (h2) - sc-401446-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYVE-1 CRISPR Activation Plasmid (h) - sc-401446-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYVE-1 CRISPR Activation Plasmid (h2) - sc-401446-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYVE-1 Lentiviral Activation Particles (h) - sc-401446-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYVE-1 Lentiviral Activation Particles (h2) - sc-401446-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LYVE-1 siRNA (h) - sc-42901 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LYVE-1 shRNA Plasmid (h) - sc-42901-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LYVE-1 shRNA (h) Lentiviral Particles - sc-42901-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU048851 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN12874 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12874 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

LYVE1 siRNA (Human) - CRH7424 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LYVE-1 RNAi - H00010894-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human LYVE1 (NM_006691.3) - SHH336239 from Creative biogene

Category siRNA
Species Reactivities Human

LYVE1 shRNA Plasmid (Human) - CHH7424 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LYVE1 miRNA 3'UTR clone - MiUTR1H-11314 from Creative biogene

Species Reactivities Human
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