RRAGB

Gene Symbol	RRAGB
Entrez Gene	10325
Alt Symbol	RAGB, bA465E19.1
Species	Human
Gene Type	protein-coding
Description	Ras-related GTP binding B
Other Description	GTP-binding protein ragB|rag B|ras-related GTP-binding protein B
Swissprots	Q8N3T0 Q15348 Q5VZM2 A8K042
Accessions	EAW93227 EAW93228 EAW93229 Q5VZM2 AK289407 BAF82096 AL831926 CAD38586 BC034726 AAH34726 BX641797 CD676755 DB246060 DB252202 EU831588 ACE87188 EU831673 ACE86507 X90530 CAA62132 XM_005261973 XP_005262030 XM_005261975 XP_005262032 XR_244464 XR_244465 XR_430513 XR_938361 NM_006064 NP_006055 NM_016656 NP_057740
Function	Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. {ECO:0000269|PubMed:18497260, ECO:0000269|PubMed:20381137, ECO:0000269|PubMed:9394008}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:7499430}. Lysosome.
Top Pathways	mTOR signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RRAGB ORF clone(NM_016656.3) - CDCH399216 from Creative Biomart Species Human Accession NM_016656.3

Human RRAGB ORF Clone(NM_006064.4) - CDCL174269 from Creative Biomart Species Human Accession NM_006064.4

Human RRAGB Gene cDNA clone plasmid - HG16568-U from Sino Biological Species Human Accession NM_006064.4

Human RRAGB Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-tagged - HG16568-CY from Sino Biological Species Human Accession NM_006064.4

Human RRAGB natural ORF mammalian expression plasmid, C-OFPSpark tag - HG16568-ACR from Sino Biological Species Human Accession NM_006064.4

Human RRAGB natural ORF mammalian expression plasmid, N-OFPSpark tag - HG16568-ANR from Sino Biological Species Human Accession NM_006064.4

Human RRAGB natural ORF mammalian expression plasmid, N-Myc tag - HG16568-NM from Sino Biological Species Human Accession NM_006064.4

Human RRAGB natural ORF mammalian expression plasmid, N-HA tag - HG16568-NY from Sino Biological Species Human Accession NM_006064.4

Human RRAGB Gene cDNA Clone (full-length ORF Clone), expression ready, C-GFPSpark-tagged - HG16568-ACG from Sino Biological Species Human Accession NM_006064.4

Human RRAGB Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-tagged - HG16568-NH from Sino Biological Species Human Accession NM_006064.4

Human RRAGB natural ORF mammalian expression plasmid, N-GFPSpark tag - HG16568-ANG from Sino Biological Species Human Accession NM_006064.4

Human RRAGB natural ORF mammalian expression plasmid, C-Flag tag - HG16568-CF from Sino Biological Species Human Accession NM_006064.4

Human RRAGB natural ORF mammalian expression plasmid, C-His tag - HG16568-CH from Sino Biological Species Human Accession NM_006064.4

Human RRAGB Gene cDNA Clone (full-length ORF Clone), expression ready, C-Myc-tagged - HG16568-CM from Sino Biological Species Human Accession NM_006064.4

Human RRAGB natural ORF mammalian expression plasmid, N-Flag tag - HG16568-NF from Sino Biological Species Human Accession NM_006064.4

Human RRAGB natural ORF mammalian expression plasmid - HG16568-UT from Sino Biological Species Human Accession NM_006064.4

human RRAGB ORF clone (NM_016656.3) - CDCH075834 from Creative biogene Species Human

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