RRAGB

Gene Symbol	RRAGB
Entrez Gene	10325
Alt Symbol	RAGB, bA465E19.1
Species	Human
Gene Type	protein-coding
Description	Ras-related GTP binding B
Other Description	GTP-binding protein ragB|rag B|ras-related GTP-binding protein B
Swissprots	Q8N3T0 Q15348 Q5VZM2 A8K042
Accessions	EAW93227 EAW93228 EAW93229 Q5VZM2 AK289407 BAF82096 AL831926 CAD38586 BC034726 AAH34726 BX641797 CD676755 DB246060 DB252202 EU831588 ACE87188 EU831673 ACE86507 X90530 CAA62132 XM_005261973 XP_005262030 XM_005261975 XP_005262032 XR_244464 XR_244465 XR_430513 XR_938361 NM_006064 NP_006055 NM_016656 NP_057740
Function	Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. {ECO:0000269|PubMed:18497260, ECO:0000269|PubMed:20381137, ECO:0000269|PubMed:9394008}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:7499430}. Lysosome.
Top Pathways	mTOR signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RRAGB full length protein - ab160946 from Abcam Category Protein Source Wheat germ Species Human

RRAGB / RAGB Antibody Blocking Peptide - LS-E6256 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RRAGB / RAGB Antibody Blocking Peptide - LS-E24066 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human RRAGB Protein - H00010325-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

RRAGB-Antibody-N-term-Blocking-Peptide - BP18936a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RRAGB / Rag B - H00010325-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RRAGB / Rag B - H00010325-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RRAGB fusion protein - Ag4116 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, T-HIS Species Human

Recombinant Human RRAGB, His-tagged - RRAGB-2441H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Ras-related GTP-binding protein B(RRAGB) - CSB-YP726126HU CSB-EP726126HU CSB-BP726126HU CSB-MP726126HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RRAGB / Rag B (transcript variant RAGBs) - TP301860 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

RRAGB Protein - NBP1-85801PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

RRAGB Peptide, Human - M34GP13618H from Creative Peptides Category Peptide Source Synthetic. Species Human

Ras-related GTP-binding protein B (RRAGB), Recombinant Protein - MBS1336092 from MyBioSource Category Protein Prices $1,140.00, $1,140.00, $1,370.00, $1,370.00, $1,820.00, $1,820.00, $2,285.00, $2,285.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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