RRAGB

Gene Symbol	RRAGB
Entrez Gene	10325
Alt Symbol	RAGB, bA465E19.1
Species	Human
Gene Type	protein-coding
Description	Ras-related GTP binding B
Other Description	GTP-binding protein ragB|rag B|ras-related GTP-binding protein B
Swissprots	Q8N3T0 Q15348 Q5VZM2 A8K042
Accessions	EAW93227 EAW93228 EAW93229 Q5VZM2 AK289407 BAF82096 AL831926 CAD38586 BC034726 AAH34726 BX641797 CD676755 DB246060 DB252202 EU831588 ACE87188 EU831673 ACE86507 X90530 CAA62132 XM_005261973 XP_005262030 XM_005261975 XP_005262032 XR_244464 XR_244465 XR_430513 XR_938361 NM_006064 NP_006055 NM_016656 NP_057740
Function	Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. {ECO:0000269|PubMed:18497260, ECO:0000269|PubMed:20381137, ECO:0000269|PubMed:9394008}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:7499430}. Lysosome.
Top Pathways	mTOR signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rag B CRISPR/Cas9 KO Plasmid (h) - sc-408810 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag B HDR Plasmid (h) - sc-408810-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag B Double Nickase Plasmid (h) - sc-408810-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag B Double Nickase Plasmid (h2) - sc-408810-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag B CRISPR Activation Plasmid (h) - sc-408810-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag B CRISPR Activation Plasmid (h2) - sc-408810-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag B Lentiviral Activation Particles (h) - sc-408810-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag B Lentiviral Activation Particles (h2) - sc-408810-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag B siRNA (h) - sc-91086 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Rag B shRNA Plasmid (h) - sc-91086-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Rag B shRNA (h) Lentiviral Particles - sc-91086-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

RRAGB RNAi - H00010325-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

RRAGB RNAi - H00010325-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU123261 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18677 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18677 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03699 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr03699

RRAGB siRNA (Human) - CRH6997 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

RRAGB - MBS8206769 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human RRAGB (NM_006064.4) - SHH399856 from Creative biogene Category siRNA Species Reactivities Human

Human RRAGB siRNA - orb267499 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

RRAGB shRNA Plasmid (Human) - CHH6997 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

RRAGB miRNA 3'UTR clone - MiUTR3H-02923 from Creative biogene Species Reactivities Human

RRAGB miRNA 3'UTR clone - MiUTR3H-02924 from Creative biogene Species Reactivities Human

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