Gene Symbol | CRYZ |
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Entrez Gene | 1429 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | crystallin, zeta (quinone reductase) |
Other Description | NADPH:quinone reductase|quinone oxidoreductase |
Swissprots | Q59EU7 Q53FT0 Q6NSK9 D3DQ76 A6NN60 Q08257 Q5HYE7 |
Accessions | AAK40311 EAX06409 EAX06410 EAX06411 EAX06412 Q08257 AB209714 BAD92951 AK123469 AK128794 AK223150 BAD96870 AK223201 BAD96921 AK314813 BC039578 AAH39578 BC070058 AAH70058 BX647883 CAI46072 BX649061 CN368109 DA256305 L13278 AAA36536 XM_005270491 XP_005270548 XM_011540747 XP_011539049 NM_001130042 NP_001123514 NM_001130043 NP_001123515 NM_001134759 NP_001128231 NM_001889 NP_001880 |
Function | Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding. {ECO:0000269|PubMed:17497241, ECO:0000269|PubMed:20103721}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20103721}. |
Tissue Specificity | Only very low amounts in the lens. |
Anti-CRYZ antibody - ab84569 from Abcam
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Anti-CRYZ antibody - ab69705 from Abcam
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Anti-CRYZ antibody - ab151490 from Abcam
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Anti-CRYZ antibody [2A9DD1] - ab110310 from Abcam
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Anti-CRYZ antibody [EPR10843(B)] - ab154842 from Abcam
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Anti-CRYZ antibody [EPR10844(B)] - ab155281 from Abcam
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Anti-CRYZ Antibody - LS-C310001 from LifeSpan Bioscience
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Anti-CRYZ Antibody - LS-C307827 from LifeSpan Bioscience
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Anti-CRYZ Antibody - LS-C310004 from LifeSpan Bioscience
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Anti-CRYZ Antibody (aa216-265) - LS-C102205 from LifeSpan Bioscience
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CRYZ Antibody - NBP1-89536 from Novus Biologicals
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CRYZ Antibody - NBP1-89533 from Novus Biologicals
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CRYZ Antibody - NBP2-16017 from Novus Biologicals
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CRYZ Antibody - NBP2-16016 from Novus Biologicals
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CRYZ Antibody - H00001429-B01P from Novus Biologicals
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CRYZ Antibody - H00001429-B01 from Novus Biologicals
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CRYZ Antibody - H00001429-A01 from Novus Biologicals
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CRYZ Antibody - H00001429-D01P from Novus Biologicals
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CRYZ Antibody - H00001429-D01 from Novus Biologicals
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Anti-CRYZ antibody produced in rabbit - HPA021921 from Sigma-Aldrich
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Anti-CRYZ antibody produced in rabbit - HPA023290 from Sigma-Aldrich
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Anti-CRYZ antibody produced in rabbit - SAB2100486 from Sigma-Aldrich
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CRYZ antibody - middle region (ARP46065_P050) - ARP46065_P050 from Aviva Systems Biology
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CRYZ antibody [N2C3] - GTX118269 from GeneTex
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CRYZ antibody - orb182774 from Biorbyt
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