| Gene Symbol | CRYZ |
|---|---|
| Entrez Gene | 1429 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | crystallin, zeta (quinone reductase) |
| Other Description | NADPH:quinone reductase|quinone oxidoreductase |
| Swissprots | Q59EU7 Q53FT0 Q6NSK9 D3DQ76 A6NN60 Q08257 Q5HYE7 |
| Accessions | AAK40311 EAX06409 EAX06410 EAX06411 EAX06412 Q08257 AB209714 BAD92951 AK123469 AK128794 AK223150 BAD96870 AK223201 BAD96921 AK314813 BC039578 AAH39578 BC070058 AAH70058 BX647883 CAI46072 BX649061 CN368109 DA256305 L13278 AAA36536 XM_005270491 XP_005270548 XM_011540747 XP_011539049 NM_001130042 NP_001123514 NM_001130043 NP_001123515 NM_001134759 NP_001128231 NM_001889 NP_001880 |
| Function | Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding. {ECO:0000269|PubMed:17497241, ECO:0000269|PubMed:20103721}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20103721}. |
| Tissue Specificity | Only very low amounts in the lens. |
Human CRYZ cDNA clone(NM_001130043.1) - CDFH004301 from Creative Biomart
|
||||
Human CRYZ cDNA clone(NM_001130042.1) - CDFH004302 from Creative Biomart
|
||||
Human CRYZ cDNA clone(NM_001134759.1) - CDFH004303 from Creative Biomart
|
||||
Human CRYZ ORF Clone(NM_001889.3) - CDCL159858 from Creative Biomart
|
||||
Human CRYZ ORF Clone(NM_001889.3) - CDCR281805 from Creative Biomart
|
||||
Human CRYZ ORF Clone(NM_001889.3) - CDCR281806 from Creative Biomart
|
||||
Human CRYZ ORF Clone(NM_001130042.1) - CDCR349387 from Creative Biomart
|
||||
Human CRYZ ORF Clone(NM_001130043.1) - CDCR349388 from Creative Biomart
|
||||
Human CRYZ ORF Clone(NM_001130043.1) - CDCR349389 from Creative Biomart
|
||||
Human CRYZ ORF Clone(NM_001130042.1) - CDCR349392 from Creative Biomart
|
||||
Human CRYZ ORF Clone(NM_001134759.1) - CDCR350103 from Creative Biomart
|
||||
Human CRYZ ORF Clone(NM_001134759.1) - CDCR350105 from Creative Biomart
|
||||
Human CRYZ ORF Clone(NM_001889.3) - CDCR281805 from Creative biogene
|
||||
Human CRYZ ORF Clone(NM_001130042.1) - CDCR349387 from Creative biogene
|
||||
Human CRYZ ORF clone (NM_001130043.1) - CDCR050950 from Creative biogene
|
||||
Human CRYZ ORF clone (NM_001134759.1) - CDCR050952 from Creative biogene
|
||||
Human CRYZ cDNA Clone(NM_001130043.1) - CDFH004301 from Creative biogene
|
||||
Human CRYZ cDNA Clone(NM_001130042.1) - CDFH004302 from Creative biogene
|
||||
Human CRYZ cDNA Clone(NM_001134759.1) - CDFH004303 from Creative biogene
|