Gene Symbol | CRYZ |
---|---|
Entrez Gene | 1429 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | crystallin, zeta (quinone reductase) |
Other Description | NADPH:quinone reductase|quinone oxidoreductase |
Swissprots | Q59EU7 Q53FT0 Q6NSK9 D3DQ76 A6NN60 Q08257 Q5HYE7 |
Accessions | AAK40311 EAX06409 EAX06410 EAX06411 EAX06412 Q08257 AB209714 BAD92951 AK123469 AK128794 AK223150 BAD96870 AK223201 BAD96921 AK314813 BC039578 AAH39578 BC070058 AAH70058 BX647883 CAI46072 BX649061 CN368109 DA256305 L13278 AAA36536 XM_005270491 XP_005270548 XM_011540747 XP_011539049 NM_001130042 NP_001123514 NM_001130043 NP_001123515 NM_001134759 NP_001128231 NM_001889 NP_001880 |
Function | Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding. {ECO:0000269|PubMed:17497241, ECO:0000269|PubMed:20103721}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20103721}. |
Tissue Specificity | Only very low amounts in the lens. |
Human CRYZ full length protein - ab158208 from Abcam
|
||||||||||
Human CRYZ full length protein - ab180303 from Abcam
|
||||||||||
Human CRYZ protein fragment - ab158209 from Abcam
|
||||||||||
CRYZ Antibody Blocking Peptide - LS-E16785 from LifeSpan Bioscience
|
||||||||||
CRYZ Recombinant Protein - H00001429-P01 from Novus Biologicals
|
||||||||||
CRYZ Partial Recombinant Protein - H00001429-Q01 from Novus Biologicals
|
||||||||||
CRYZ-Antibody-Center-Blocking-Peptide - BP6566c from Abgent, a WuXi AppTec company
|
||||||||||
CRYZ-Antibody-N-term-Blocking-Peptide - BP6566a from Abgent, a WuXi AppTec company
|
||||||||||
CRYZ protein (His tag) - 80R-3883 from Fitzgerald
|
||||||||||
Zeta-crystallin (1-329, His-tag) - AR51570PU-N from Acris Antibodies
|
||||||||||
Zeta-crystallin (1-329, His-tag) - AR51570PU-S from Acris Antibodies
|
||||||||||
Zeta-crystallin - H00001429-P01-10 from Acris Antibodies
|
||||||||||
Zeta-crystallin - H00001429-P01-25 from Acris Antibodies
|
||||||||||
Zeta-crystallin - H00001429-Q01-10 from Acris Antibodies
|
||||||||||
Zeta-crystallin - H00001429-Q01-25 from Acris Antibodies
|
||||||||||
CRYZ, 1-329aa, Human, His tag, E.coli - 01-P2750 from ARP American Research Products
|
||||||||||
Recombinant Human CRYZ, His-tagged - CRYZ-257H from Creative Biomart
|
||||||||||
Recombinant Human Quinone oxidoreductase(CRYZ) - CSB-YP600843HU CSB-EP600843HU CSB-BP600843HU CSB-MP600843HU from Cusabio
|
||||||||||
CRYZ, 1-329aa, Human, His tag, E.coli - ATGP2750 from ATGen
|
||||||||||
CRYZ Recombinant Protein Antigen - NBP1-89536PEP from Novus Biologicals
|
||||||||||
CRYZ Recombinant Protein Antigen - NBP1-89533PEP from Novus Biologicals
|
||||||||||
CRYZ-Blocking-Peptide-C-term - BP21584b from Abgent, a WuXi AppTec company
|
||||||||||
CRYZ Peptide, Human - M34GP03688H from Creative Peptides
|
||||||||||
Human CRYZ protein - orb259860 from Biorbyt
|
||||||||||
CRYZ Recombinant Protein - NBP2-51762 from Novus Biologicals
|