TANK

Gene Symbol	TANK
Entrez Gene	10010
Alt Symbol	I-TRAF, ITRAF, TRAF2
Species	Human
Gene Type	protein-coding
Description	TRAF family member-associated NFKB activator
Other Description	TRAF family member-associated NF-kappa-B activator|TRAF-interacting protein
Swissprots	Q92844 Q7Z4J6 D3DPB5 Q92885
Accessions	AAX88939 AAY14785 EAX11374 EAX11375 EAX11376 EAX11377 Q92844 AK313096 BAG35920 BC003388 AAH03388 BC067779 AAH67779 BT009855 AAP88857 U59863 AAC50681 U63830 AAC50770 XM_005246207 XP_005246264 XM_005246208 XP_005246265 XM_005246210 XP_005246267 XM_005246211 XP_005246268 XM_011510455 XP_011508757 NM_004180 NP_004171 NM_133484 NP_597841 NM_001199135 NP_001186064
Function	Adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. Acts as a regulator of TRAF function by maintaining them in a latent state. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May control negatively TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. {ECO:0000269|PubMed:12133833, ECO:0000269|PubMed:21931631}.
Subcellular Location	Cytoplasm.
Tissue Specificity	Ubiquitous.
Top Pathways	RIG-I-like receptor signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TANK full length protein - ab132132 from Abcam Category Protein Source Wheat germ Species Human

Human TANK full length protein - ab140046 from Abcam Category Protein Source E. coli Species Human

Human TANK peptide - ab51555 from Abcam Category Peptide Species Human

Human TANK peptide - ab51556 from Abcam Category Peptide Species Human

Human TANK peptide - ab92908 from Abcam Category Peptide Species Human

Human TANK protein fragment - ab84185 from Abcam Category Protein Source E. coli Species Human

Human TANK protein fragment - ab117667 from Abcam Category Protein Source E. coli Species Human

TANK Antibody Blocking Peptide - LS-E10517 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TANK Antibody Blocking Peptide - LS-E30257 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TANK Antibody Blocking Peptide - LS-E30256 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TANK Antibody Blocking Peptide - LS-E8012 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TANK Antibody Blocking Peptide - LS-E11285 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TANK Antibody Blocking Peptide - LS-E13805 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TANK Antibody Blocking Peptide - LS-E13806 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TANK Recombinant Protein - H00010010-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human TANK Protein - NBC1-22948 from Novus Biologicals Category Protein Prices $279.00 Sizes 100 µg Source E. coli Species Human

Recombinant Human TANK Protein - NBP2-22874 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

TANK Blocking Peptide - NBP1-76717PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

TANK Blocking Peptide - NBP1-76716PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

TANK-Antibody-Center-Blocking-peptide - BP5860c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant human TRAF family member-associated NF-kappa-B activator (OPCA00234) - OPCA00234 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Recombinant human TRAF family member-associated NF-kappa-B activator (OPCA01309) - OPCA01309 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human TANK protein - orb169392 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli

Human TANK protein - orb246006 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human TANK protein - orb244572 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

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