OPRD1

Gene Symbol OPRD1
Entrez Gene 4985
Alt Symbol OPRD
Species Human
Gene Type protein-coding
Description opioid receptor, delta 1
Other Description D-OR-1|DOR-1|delta opioid receptor 1|delta-type opioid receptor
Swissprots B5B0B8 P41143
Accessions EAX07672 P41143 BC111838 AAI11839 BF434068 EF057065 ABO25742 EU883570 ACG60644 U07882 AAA18789 U10504 AAA83426 NM_000911 NP_000902
Function G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine. {ECO:0000269|PubMed:22184124, ECO:0000269|PubMed:7808419, ECO:0000269|PubMed:8201839}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:22184124, ECO:0000269|PubMed:7808419, ECO:0000269|PubMed:8201839}; Multi- pass membrane protein {ECO:0000269|PubMed:22184124, ECO:0000269|PubMed:7808419, ECO:0000269|PubMed:8201839}.
Tissue Specificity Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes. {ECO:0000269|PubMed:22417668, ECO:0000269|PubMed:7808419}.
Top Pathways cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction

OPRD1 overexpression lysate - LY400330 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

OPRD1 293 Cell Lysate - 400364 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

delta Opioid R/OPRD1 Overexpression Lysate (Native) - NBL1-13942 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Delta Opioid Receptor Overexpression Lysate (Adult Normal) [NBL1-13942] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Delta Opioid Receptor.

OPRD1 Over-expression Lysate Product - GWB-2BD3FD from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human
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