OPRD1

Gene Symbol	OPRD1
Entrez Gene	4985
Alt Symbol	OPRD
Species	Human
Gene Type	protein-coding
Description	opioid receptor, delta 1
Other Description	D-OR-1|DOR-1|delta opioid receptor 1|delta-type opioid receptor
Swissprots	B5B0B8 P41143
Accessions	EAX07672 P41143 BC111838 AAI11839 BF434068 EF057065 ABO25742 EU883570 ACG60644 U07882 AAA18789 U10504 AAA83426 NM_000911 NP_000902
Function	G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine. {ECO:0000269|PubMed:22184124, ECO:0000269|PubMed:7808419, ECO:0000269|PubMed:8201839}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:22184124, ECO:0000269|PubMed:7808419, ECO:0000269|PubMed:8201839}; Multi- pass membrane protein {ECO:0000269|PubMed:22184124, ECO:0000269|PubMed:7808419, ECO:0000269|PubMed:8201839}.
Tissue Specificity	Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes. {ECO:0000269|PubMed:22417668, ECO:0000269|PubMed:7808419}.
Top Pathways	cGMP-PKG signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Delta Opioid Receptor peptide - ab38192 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Delta Opioid Receptor peptide - ab38193 from Abcam Category Peptide Prices $181.00 Sizes 20 µg

OPRD1 / Delta Opioid Receptor Antibody Blocking Peptide - LS-E28522 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

OPRD1 / Delta Opioid Receptor Antibody Blocking Peptide - LS-E28524 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

OPRD1 / Delta Opioid Receptor Antibody Blocking Peptide - LS-E28527 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

OPRD1 / Delta Opioid Receptor Antibody Blocking Peptide - LS-E28525 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ChemiSCREEN™ Human δ Opioid Receptor Membrane Preparation - HTS100M from EMD Millipore Prices $596.00 Sizes 200 units Species Human

Delta Opioid Receptor Blocking Peptide - CBP1838 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Pig

DOR-1 (R356) Peptide - BS1814P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

DOR-1 (F345) Peptide - BS3179P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Delta Opioid Receptor (pS363) Blocking Peptide - abx161694 from Abbexa Category Peptide Species Human, Mouse, Rat, Pig

OPRD1 Protein - abx163635 from Abbexa Category Protein Species Rat

OPRD1, Peptide - MBS428191 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat

delta Opioid R/OPRD1 Recombinant Protein Antigen - NBP1-87471PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Delta Opioid Receptor Peptide (OEMA00027) - OEMA00027 from Aviva Systems Biology Category Peptide Prices $445.00 Sizes 1 mg

Delta Opioid Receptor (pS363) Blocking Peptide - CBP4483 from Cohesion Biosciences Category Peptide Prices $150.00, $450.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Pig

OPRD1 (Phospho-S363) Blocking Peptide - orb392828 from Biorbyt Category Peptide Prices $340.00, $587.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Pig

Delta-type opioid receptor (OPRD1), Recombinant Protein - MBS956112 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Delta-type opioid receptor (OPRD1), Recombinant Protein - MBS7024620 from MyBioSource Category Protein Prices $1,180.00, $2,165.00, $3,375.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

OPRD1 peptide - orb217701 from Biorbyt Category Peptide Species Human, Mouse, Rat

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