PROKR1

Gene Symbol PROKR1
Entrez Gene 10887
Alt Symbol GPR73, GPR73a, PKR1, ZAQ
Species Human
Gene Type protein-coding
Description prokineticin receptor 1
Other Description G protein-coupled receptor 73|G protein-coupled receptor ZAQ|G-protein coupled receptor 73|G-protein coupled receptor ZAQ|PK-R1
Swissprots Q8NFJ7 A5JUU2 Q53QT9 Q8TCW9
Accessions AAY24114 EAW99869 Q8TCW9 AB084080 BAC24021 AF506287 AAM48127 AY089976 AAM11892 BC100960 AAI00961 EF577399 ABQ52419 NM_138964 NP_620414
Function Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy. {ECO:0000269|PubMed:18339712}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Localizes to glandular epithelium, stroma and vascular endothelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the stomach, throughout the small intestine, colon, rectum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary, brain, spleen, prostate and pancreas. {ECO:0000269|PubMed:18339712}.

PKR1 (T-20) - sc-54313 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PKR1 (N-18) - sc-54311 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-GPR73A antibody - ab42804 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
ab42804 staining GPR73A in umbilical cord (top) and placental villi (bottom) by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). On the right is a negative control image.

Anti-GPR73A antibody - ab75104 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GPR73A antibody (ab75104) at 1/500 dilutionLane 1 : Extracts from COLO cellsLane 2 : Extracts from COLO cells with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-GPR73A antibody - N-terminal - ab181765 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical staining of fasciculate cells labeling GPR73A with ab181765 at 1/100 dilution

Anti-GPR73A antibody - N-terminal - ab140976 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skeletal muscle tissue labeling GPR73A with ab140976 at 16 µg/ml.

Anti-PROKR1 Antibody - LS-C66876 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PROKR1 Antibody (N-Terminus) - LS-C153522 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PROKR1 Antibody (aa356-393) - LS-C190866 from LifeSpan Bioscience

Prices $740.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-PROKR1 Antibody (C-Terminus) IHC-plus™ - LS-A3152 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PROKR1 antibody LS-A3152 IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-PROKR1 Antibody (aa19-68) - LS-C120941 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from COLO205 cells, using PKR1 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-PROKR1 Antibody (N-Terminus) IHC-plus™ - LS-A6684 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PROKR1 antibody LS-A6684 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-PROKR1 Antibody (N-Terminus) - LS-C144644 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PKN1 Antibody - NB100-56159 from Novus Biologicals

Prices $129.00, $199.00
Sizes 25 µl, 50 µl
Host Rabbit
Clonality Polyclonal

Prokineticin R1/PROKR1 Antibody - NBP2-15201 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Prokineticin R1/PROKR1 Antibody (420849) - MAB4655 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 420849
Flow Cytometry Prokineticin R1/PROKR1 Antibody (420849)

Prokineticin R1/PROKR1 Antibody - NBP1-00986 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PROKR1 Antibody [NBP1-00986] Extracts from raw264.7 cells.

Prokineticin R1/PROKR1 Antibody - NLS3152 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Prokineticin R1/PROKR1 Antibody [NLS3152] - Analysis of anti-PROKR1 antibody with human colon at 13 ug/ml.

Anti-PROKR1 antibody produced in rabbit - HPA029396 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PROKR1: <B>Cat. No. HPA029396</B>: Immunohistochemical staining of human small intestine shows strong cytoplasmic positivity in paneth cells.

Anti-PROKR1 (36-48) antibody produced in rabbit - R5156 from Sigma-Aldrich

Prices $342.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-PROKR1 (36-48) (RB): <B>Cat. No. R5156</B>: Immunofluorescence of HUVEC cells using PROKR1 (36-48) (RB), <B>Cat. No. R5156</B> (red) at a 1:100 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used.<BR/>Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-PKR1, N-Terminal antibody produced in rabbit - SAB4500174 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PKR1, N-Terminal: <B>Cat. No. SAB4500174</B>: Immunoblotting analysis of extracts from COLO cells, using Anti-PKR1, N-Terminal antibody. The lane on the left was treated with the Anti-PKR1, N-Terminal antibody. The lane on the right (negative control) was treated with both Anti-PKR1, N-Terminal antibody and the synthesized immunogen peptide.

GPR73A antibody [N1], N-term - GTX108124 from GeneTex

Host Rabbit
Clonality Polyclonal

GPR73A antibody - GTX13084 from GeneTex

Prices $319.00
Sizes 25 μg
Host Rabbit
Clonality Polyclonal

Human Prokineticin R1/PKR1 Antibody - MAB4655 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clone 420849
Detection of Prokineticin R1/PKR1 in Human Monocytes by Flow Cytometry. Human blood‑derived monocytes were stained with Human Prokineticin R1/PKR1 Monoclonal Antibody (Catalog # MAB4655, filled histogram) or isotype control antibody (Catalog # MAB0041 , open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab') 2 Secondary Antibody (Catalog # F0101B ).

Human Prokineticin R1 MAb (Clone 420849), Mouse IgG2B - MAB4655-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 420849
Detection of Prokineticin R1/PKR1 in Human Monocytes by Flow Cytometry. Human blood‑derived monocytes were stained with Human Prokineticin R1/PKR1 Monoclonal Antibody (Catalog # MAB4655, filled histogram) or isotype control antibody (Catalog # MAB0041, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab')2 Secondary Antibody (Catalog # F0101B).
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